Patients with overactive bladder syndrome are significantly affected by their symptoms of urinary urgency, frequency, nocturia, and urge urinary incontinence. The measurement of this impact on their lives is probably best appreciated by health-related quality-of-life instruments and global subjective assessments of patient satisfaction. Treatments for this syndrome should offer more than just e...

Overactive bladder is a highly prevalent disorder with a significant impact on quality of life. Antimuscarinic agents are commonly used, but persistence is limited due to unsatisfactory efficacy and/or tolerability. Mirabegron is the first beta-3 adrenoceptor agonist approved for the treatment of overactive bladder syndrome. This paper reviews the pharmacology, mechanism of action, efficacy, an...

overactive bladder (oab) is a disabling disorder. treatment of cases with oab includes behavioral, pharmacological, surgical interventions and peripheral electrical stimulation. the goal of this study was to determine effects of posterior tibial nerve stimulation on sexual function and pelvic disorders in women with overactive bladder (oab). fifty women were randomly assigned to ptns (posterior...

BACKGROUND In earlier studies, one in six adults had overactive bladder which may impair quality of life. However, earlier studies have either not been population-based or have suffered from methodological limitations. Our aim was to assess the prevalence of overactive bladder symptoms, based on a representative study population and using consistent definitions and exclusions. METHODOLOGY/PRI...

BACKGROUND Although having a regular primary care provider is noted to be beneficial to health, doctor shopping has been documented as a common treatment seeking behavior among chronically ill patients in different countries. However, little research has been conducted into the reasons behind doctor shopping behavior among patients with overactive bladder, and even less into how this behavior r...

BACKGROUND Overactive bladder syndrome is a symptom-based clinical diagnosis. It is characterised by urinary urgency, frequency and nocturia, with or without urge urinary incontinence. These symptoms can often be managed in the primary care setting. OBJECTIVE This article provides a review on overactive bladder syndrome and provides advice on management for the general practitioner. DISCUSS...

Overactive bladder (OAB) is a common problem whose prevalence increases with advancing age and compromises ­health-related­quality­of­life.­Tolterodine­was­the­first­antimuscarinic­drug­specifically­designed­to­treat­OAB. Through­MEDLINE,­we­reviewed­articles,­standardization­reports­and­meeting­abstracts,­published­between­2001­and­2011,­on­the­efficacy and tolerability of Tolterodine extended...

PURPOSE Cystoscopic intradetrusor injection of botulinum toxin has helped patients with refractory overactive bladder but with the increased risks of urinary tract infection and urinary retention. We assessed whether catheter instillation of 200 U onabotulinumtoxinA formulated with liposomes is safe and effective for the treatment of overactive bladder. MATERIALS AND METHODS This 2-center, do...