Background: Polycystic Ovarian Syndrome (PCOS) is a pro-inflammatory condition that supports the development of metabolic aberration and ovarian dysfunction. Chronic inflammation and the increased levels of androgens in this group of patients and their impact on the immune system may increase the risk of developing malignancies, including ovarian cancer. Thus, we interacted ovarian tumor cells ...

there is a continuing need to identify new agents that are active in ovarian cancer. etoposide is a derivative of the plant alkaloid epipodophyllotoxin. the availability of etoposide in oral preparation allows prolonged administration by the oral route. in this study, activity and toxicity of etoposide in women with recurrent ovarian cancer are described from a case series of women with recurre...

Background: To assess the effectiveness of repeated transvaginal ultrasound-guided ovarian interstitial laser treatment in the management of anovulatory patients with polycystic ovary syndrome (PCOS). Materials and Methods: A retrospective study was performed in our department on 27 anovulatory PCOS women who failed to respond to the first ultrasound-guided transvaginal ovarian interstitial las...

BACKGROUND With the occasional reports of unexpectedly poor ovarian response to controlled ovarian hyperstimulation (COH) for IVF in young normally cyclic women in mind, we studied age-related ovarian response to COH in a group of women who underwent standard IVF. METHODS Ovarian response to COH was defined as the number of follicles > or = 14 mm on the day of hCG administration. Ovarian resp...

BACKGROUND This secondary analysis aimed to identify predictors of low (<6 oocytes retrieved) and high ovarian response (>18 oocytes retrieved) in IVF patients undergoing controlled ovarian stimulation with corifollitropin alfa in a gonadotropin-releasing hormone (GnRH) antagonist protocol. METHODS Statistical model building for high and low ovarian response was based on the 150 μg corifollit...

Evaluation of calcified metastatic lesions by conventional imaging can be challenging. Ovarian cancer metastases can present with calcification which might increase in size and number following therapy. It is not entirely clear whether these calcifications are associated with tumor response or disease progression. Calcified lesions which do not change in size or configuration are particularly p...

Background: This study intends to present the role of rescue in vitro maturation (IVM) in polycystic ovarian syndrome(PCOS) patients undergoing in vitro fertilization (IVF) treatment who have inappropriate responses to ovarianstimulation.Materials and Methods: This was a retrospective case series study of five PCOS patients undergoing IVF treatmentconsidered for cycle ca...

Infertility is a very disastrous side effect in young females, especially in traditional male-dominated societies. The aim of this talk is to discuss the possible ways for fertility preservation in both man and woman. Another aspect is to how to predict women at threat of premature ovarian failure. It will also illustrate the association of cytochrome P450 (CYP2C19) polymorphism with ovarian to...

we examined the demographic characteristics of couples, ovarian response and sperm quality to determine the predictors of clinical fertilization in ivf cycles. a descriptive and analytic study was conducted using data and biologic specimens obtained fatemeh-alzahra of babol infertility center from 2004 to 2005. only data from 315 women who had medical indication for conventional ivf treatment w...

vascularization of the follicle may play a role in its maturation and aspirin seems to increase this vascularization.in this investigation we have studied the effects of low-dose aspirin on ovarian and uterine response, implantation and pregnancy rates in patients undergoing intracytoplasmic sperm injection (icsi). this prospective semirandomized, double-blind, placebo-controlled study was unde...