premature ovarian failure (pof) is a heterogeneous syndrome with several causative factors. autoimmune mechanisms are involved in pathogenesis of 4-30 % of pof cases. the present review focuses on the role of autoimmunity in the pathophysiology of pof. the evidences for an autoimmune etiology are: demonstration of ovarian autoantibodies, the presence of lymphocytic oophoritis, and association w...

background: previous studies have reported the antifertility activities of sulfonamides. this study was designed to evaluate the effects of co-trimoxazole and its co-administration with folic acid on ovarian tissue in female rats. methods: a total of 54 rats were randomly divided into 9 groups (n=6) . group i served as the control and group ii (vehicle) received saline. other groups, iii to ix,...

background: the best management for an ovarian mass is provided by appropriate prediction of malignancy. the aim of our study is to construct and validate a new malignancy probability score based on four simple sonographic findings and age. methods: in a cross sectional study; histopathological files of 3303 ovarian mass patients and tertiary hospitals, have reviewed within 6 years (2000-2006)....

in the present report, diagnosis and treatment of a case with follicular ovarian cysts in a 5-year-old persian queen cat is described. in response to palpation of spines, the queen cat presented herself in lordosis and danced up and down with her rear legs. trans-abdominal ultrasonography examination showed 2 cysts  in the left ovary of the queen. serum estrogen assay indicated elevated level o...

background: the purpose of this study was to compare the three different strategies, intravenous (iv) hydroxylethyl starch (hes), iv human albumin (ha), and oral cabergoline (cb) in the prevention of ovarian hyperstimulation syndrome (ohss). materials and methods: in this prospective randomized clinical trial, 91 women at high risk of developing ohss were allocated into the three groups, group ...

background: the predictive roles of follicle stimulating hormone (fsh), anti-mullerian hormone (amh) and antral follicle count (afc) as ovarian reserve markers in women with different age groups are not established well. objective: this study compares the value of fsh, amh and afc at the time of     in vitro fertilization (ivf) treatment in different age groups. materials and methods: in this c...

background: this study was undertaken to evaluate the role of day 3 fsh/lh ratio and day 3 lh level as predictors of ivf cycle outcomes. methods: this prospective observational study was undertaken in the ivf and reproductive biology centre and lok nayak hospital, affiliated to maulana azad medical college, in new delhi, india. the study included 105 women who underwent controlled ovarian hyper...

objective: the study assessed the efficacy of low dose ketoconazole in addition to clomiphene citrate ( cc) and hmg on ovulation induction. materials and methods: a double blind, randomized, clinical trial was performed on fifty infertile patients with pcos who had failed to respond to a daily dose of hmg and 100 mg cc for controlled ovarian hyperstimulation in vali-e-asr reproductive health re...