[1] It is widely accepted that the ionosphere is an important source of ions in the magnetosphere and until recently this population has largely been neglected from many global simulations. In this study, a causally regulated cusp O outflow is added to the multifluid version of the Lyon‐Fedder‐Mobarry (LFM) global simulation. The cusp outflow algorithm uses empirical relationships to regulate t...

Understanding the variations of streamflow of rivers is an important prerequisite for designing hydraulic structures as well as managing surface water resources in basins. An overview of the impact of climate change on the streamflow in the Hablehroud River, the main river of a semi-arid basin in north-central Iran, is provided. Using the LARS-WG statistical downscaling model, the outputs of Ha...

In the study, Drainmod model was used to compare measured water table depth fluctuations on the farm with those simulated by the model, also comparison of measured drainage outflow of the farm drains and model simulated was investigated. This study was made in a part of the Irrigation and Drainage Network of ABADAN Date palms. By statistical analysis of the measured and predicted water table de...

It is important to know the drug distribution following administration of drug in order to properly treat with adequate dosage and thus, avoid damage to tissues due to excessive high concentrations. A computer model was developed to determine drug distribution by convective-diffusive transport processes in a rabbit eye. When compared with pure diffusion within vitreous, the ratio of the amount ...

Visual impairment due to glaucoma currently impacts 70 million people worldwide. While disease progression can be slowed or stopped with effective lowering of intraocular pressure, current medical treatments are often inadequate. Fortunately, three new classes of therapeutics that target the diseased conventional outflow tissue responsible for ocular hypertension are in the final stages of huma...

Alluvial aquifers in mountainous regions cover typically a limited area. Their contribution to catchment storage and outflow is rarely isolated; alluvial groundwater discharge under gauging stations is generally assumed negligible; and hydrological models tend to lump alluvial storage with other units. The role of alluvial aquifers remains therefore unclear: can they contribute significantly to...

The effects of bimatoprost on aqueous humor dynamics were quantified in monkey eyes. Uveoscleral outflow was measured by the anterior chamber perfusion method, using FITC-dextran. Total outflow facility was determined by the two-level constant pressure method. Aqueous flow was measured with a scanning ocular fluorophotometer. Uveoscleral outflow was 0.96 +/- 0.19 muL min(-1) in vehicle-treated ...

AIMS This study investigated the clinical and physiological significance of the dynamic left ventricle outflow gradient observed in some patients during dobutamine stress echocardiography. METHODS Three hundred and ninety-four consecutive patients completed dobutamine stress echocardiography using Doppler echocardiography to assess the presence of myocardial ischaemia and left ventricular out...

PURPOSE To test the hypothesis that extracellular matrix turnover, mediated by the matrix metalloproteinases, modulates aqueous humor outflow facility in a human outflow model. METHODS Matrix metalloproteinase activity was manipulated and outflow facility evaluated using perfused human anterior segment organ culture. Purified matrix metalloproteinases, tissue inhibitors of metalloproteinases ...