نتایج جستجو برای: osteoclasts

تعداد نتایج: 6297  

Journal: :iranian journal of basic medical sciences 0
li-qun xiao department of stomatology, the first college of clinical medical science of china three gorges university, yichang central people's hospital, yichang 443003, china hong-tao wang department of stomatology, the first college of clinical medical science of china three gorges university, yichang central people's hospital, yichang 443003, china yu-lan li department of stomatology, the first college of clinical medical science of china three gorges university, yichang central people's hospital, yichang 443003, china qing zeng department of stomatology, the first college of clinical medical science of china three gorges university, yichang central people's hospital, yichang 443003, china e zhou department of stomatology, the first college of clinical medical science of china three gorges university, yichang central people's hospital, yichang 443003, china xia ni department of stomatology, the first college of clinical medical science of china three gorges university, yichang central people's hospital, yichang 443003, china

objective(s): salvia miltiorrhiza (sm) is a popular and classic herb in traditional chineses medicines. the objective is to confirm the effects of aqueous extract of s. miltiorrhiza (esm) and its main ingredient on the promotion of orthodontic tooth movement and healing of periodontal ligament in rat. materials and methods: male sprague-dawley rats (n= 150) were divided into five groups: model ...

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2003
Hiroshi Kajiya Fujio Okamoto Hidefumi Fukushima Keisuke Takada Koji Okabe Hidefumi Fuku

Kajiya, Hiroshi, Fujio Okamoto, Hidefumi Fukushima, Keisuke Takada, and Koji Okabe. Mechanism and role of high-potassium-induced reduction of intracellular Ca2 concentration in rat osteoclasts. Am J Physiol Cell Physiol 285: C457–C466, 2003. First published April 9, 2003; 10.1152/ajpcell.00033.2003.—Osteoclasts are multinucleated, bone-resorbing cells that show structural and functional differe...

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Journal: :Biochemical and biophysical research communications 2009
Xiumin Lu Nan Su Jing Yang Wei Huang Can Li Ling Zhao Qifen He Xiaolan Du Yue Shen Bo Chen Lin Chen

To elucidate the direct role and mechanism of FGFR1 signaling in the differentiation and activation of osteoclasts, we conditionally inactivated FGFR1 in bone marrow monocytes and mature osteoclasts of mice. Mice deficient in FGFR1 (Fgfr1(-/-)) exhibited misregulated bone remodeling with reduced osteoclast number and impaired osteoclast function. In vitro assay demonstrated that the number of t...

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2004
Frédéric Saltel Olivier Destaing Frédéric Bard Diane Eichert Pierre Jurdic

The actin cytoskeleton is essential for osteoclasts main function, bone resorption. Two different organizations of actin have been described in osteoclasts, the podosomes belt corresponding to numerous F-actin columns arranged at the cell periphery, and the sealing zone defined as a unique large band of actin. To compare the role of these two different actin organizations, we imaged osteoclasts...

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Journal: :Japanese Journal of Clinical Immunology 2017

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Journal: :The Anatomical Record 1917

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2012
Zachary S. Buchwald Jennifer R. Kiesel Richard DiPaolo Meghana S. Pagadala Rajeev Aurora

BACKGROUND Osteoclasts are the body's sole bone resorbing cells. Cytokines produced by pro-inflammatory effector T-cells (T(EFF)) increase bone resorption by osteoclasts. Prolonged exposure to the T(EFF) produced cytokines leads to bone erosion diseases such as osteoporosis and rheumatoid arthritis. The crosstalk between T-cells and osteoclasts has been termed osteoimmunology. We have previousl...

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Journal: :BoneKEy Reports 2012

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Journal: :Journal of Experimental Medicine 2005

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Journal: :Journal of Bone and Mineral Research 2009

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