Osseous metaplasia has recently been described in several cases of nephrogenic systemic fibrosis, sometimes in association with unusual clinical features such as painful hyperkeratotic spicules, palpable bony masses, and disease regression. Some authors have suggested that it may mainly occur late in the disease course or even be a marker for involuting nephrogenic systemic fibrosis. Here, we p...

Subpontic osseous hyperplasia is a relatively uncommon benign submucosal mass of normal bone found beneath a pontic. Three cases of mandibular subpontic osseous hyperplasia are described, adding to the 40 existing cases in the English-language literature. Subpontic osseous hyperplasia may represent a unique reactive osseous metaplasia in the subpontic region, with chronic stimuli and functional...

Heterotopic bone is rarely found in the gastrointestinal tract. In the majority of reported cases, it was associatedwith malignant lesions [1,2], Peutz–Jeghers syndrome [3], and more rarely with inflammatory colonic polyps [4]. On reviewing the literature, we found only two cases of metaplastic bone accompanying hyperplastic gastric mucosa [5,6], and no case report of osseous metaplasia in gast...

Osseous metaplasia should be kept in mind as a rare cause of failure to conceive, even in patients with primary infertility. We report a case of osseous metaplasia of the endometrium as a cause of primary infertility and present a literature review. The condition may be more common than expected or generally accepted, and should be kept in mind even in patients with primary infertility. Hystero...

Osseous metaplasia (OM) is rarely observed in colorectal cancer (incidence < 0.4% in rectal cancer), where it has a non-specific clinical presentation and unknown pathogenesis. Here, we report three cases of colorectal carcinoma with OM and propose a new hypothesis. All three patients (two males and one female) were Chinese and had different sites of colorectal carcinoma with OM: rectum, sigmoi...