The internal and external mechanical environment plays an important role in tumorogenesis. As a proxy of avascular early state tumor, we use multicellular spheroids, composite material made cells, extracellular matrix permeating fluid. We characterize its effective rheology at the timescale minutes to hours by compressing aggregates with osmotic shocks modeling experimental results active poroe...

Aimed at providing a contribution to the optimization of cryopreservation processes, the present work focuses on the osmotic behavior of human mesenchymal stem cells (hMSCs). Once isolated from the umbilical cord blood (UCB) of three different donors, hMSCs were characterized in terms of size distribution and their osmotic properties suitably evaluated through the exposure to hypertonic and iso...

Adaptation is an important property of living organisms enabling them to cope with environmental stress and maintaining homeostasis. Adaptation is mediated by signaling pathways responding to different stimuli. Those signaling pathways might communicate in order to orchestrate the cellular response to multiple simultaneous stimuli, a phenomenon called crosstalk. Here, we investigate possible me...

Osmotic demyelination syndrome (ODS) is a condition which occurs due to rapid osmotic changes result in myelinolysis of the nervous system. Uncommonly could involve areas beyond pons resulting extrapontine (EPM). We report 70-year-old gentleman who presented with 2-week history reduced interaction and altered behavior parkinsonism following oral correction severe hyponatraemia. Magnetic resonan...

By use of a micro technique for producing extracts of spinach mesophyll cells, chloroplasts were isolated in a state wherein they displayed microscopically visible, reversible osmotic properties. Swollen spherical chloroplasts treated with hypertonic sucrose or mannitol media, but not NaCl, could be shrunken to a state resembling their disk appearance in living cells. Reversible osmotic behavio...

-The crystalline and osmotic swelling of N~, Cs-, Mgand Ca-montmorillonite has been measured in dimethyl sulphoxide and in formamide, N-methyl formamide, dimethyl formamide, N-methyl acetamide and dimethyl acetamide. These liquids have similar dipole moments but their relative permittivities vary appreciably from values less than water to values greater than water. Na montmorillonite exhibits o...