Small insertions were made independently at each of four unique restriction sites on African cassava mosaic virus (ACMV) DNA A to disrupt the three overlapping complementary-sense open reading frames (ORFs) herein designated AC1, AC2 and AC3. The DNA A mutants were assayed for their infectivity by agroinoculation of monomeric constructs to Nicotiana benthamiana plants containing chromosomal ins...

DURING the spring and early summer of 1955 an unusually large number of cases of orf were seen in patients attending the various skin clinics in Northern Ireland. The condition aroused considerable interest, and it is hoped that these notes may prove helpful to local practitioners. Orf is an infective disease, caused by a filtrable virus of the pox group, affecting commonly sheep and goats. The...

Background and Aims: Newcastle disease virus (NDV) is one of the major pathogen in poultry. Vaccination is intended to control the disease as an effective solution nevertheless this virus is a growing threat to the poultry industry. F gene open reading frame (ORF) from NDV is 1650 bp, encoding a protein of 553 amino acids that can induce protective immunity alone. The F glycoprotein on the surf...

herpes simplex virus type-1 (hsv-1) causes a variety of diseases in human. this virus is a neurotropic pathogen of human that establishes latent infection in the sensory ganglia innervating the site of primary infection. a number of genes including icp34.5 control hsv-1 pathogenicity and icp34.5 has been identified as hsv-1 virulence gene. open reading frame p (orf p) is also a hsv-1 gene that ...

This is the first report of sequence from Fiji disease fijivirus (FDV), the type member of the genus Fijivirus of the family Reoviridae. FDV genome segment (S9) comprised 1843 nt and contained two non-overlapping ORFs, separated by a 57 nt intergenic region. S9 ORF 1 comprised 1008 nt and encoded a 335-amino-acid polypeptide (predicted molecular mass 38.6 kDa), while ORF 2 comprised 627 nt and ...

EM: erythema multiforme INTRODUCTION Orf, also known as ecthyma contagiosum, contagious pustular dermatitis, infectious pustular dermatosis, ovine pustular dermatitis, and sore mouth, is a viral zoonotic disease resulting from the direct or indirect contact of damaged skin with infected animals. The virus is endemic in sheep and goats worldwide and manifests as an acute contagious skin conditio...

aims: infection with parapoxvirus is an occupational hazard of farm workers, abattoir workers, veterinarians, and others with frequent exposure to sheep, cattle, or goats. the aim of this study was to determine the risk working groups in kashan city, iran. patients & methods: this case series study was performed in the private clinic of dr. afzali in kashan region, iran during 2000-13. diagnosi...

independent replicate experiments. Deletion of these genes affects the fitness of mutant strains in iron deficiency. The requirement for growth of each gene was quantified as a log 2 ratio of growth of the corresponding mutant strain in YPD with BPS compared to YPD alone. The log 2 fitness represents the average of the significant values in these experiments. A negative value indicates sensitiv...

Herpes simplex virus type-1 (HSV-1) causes a variety of diseases in human. This virus is a neurotropic pathogen of human that establishes latent infection in the sensory ganglia innervating the site of primary infection. A number of genes including ICP34.5 control HSV-1 pathogenicity and ICP34.5 has been identified as HSV-1 virulence gene. Open reading frame P (ORF P) is also a HSV-1 gene that ...