For industrially manufactured pharmaceutical dosage forms, product quality tests and performance tests are required to ascertain the quality of the final product. Current compendial requirements specify a disintegration and/or a dissolution test to check the quality of oral solid dosage forms. These requirements led to a number of compendial monographs for individual products and, at times, the...

----------------------------RECENT MAJOR CHANGES--------------------­ Addition of new dosage strength: ARICEPT 23 mg ----------------------------INDICATIONS AND USAGE---------------------­ ARICEPT is an acetylcholinesterase inhibitor indicated for the treatment of dementia of the Alzheimer’s type. Efficacy has been demonstrated in patients with mild, moderate, and severe Alzheimer’s Disease (1.0).

Objective of this study was to formulate directly compressible orally disintegrating tablets of Cinnarizine with sufficient mechanical integrity, content uniformity, and acceptable palatability to assist patients of any age group for easy administration. Effect of varying concentrations of different superdisintegrants such as Agar, gum karaya, platago ovata on disintegration time was studied. T...