نتایج جستجو برای: oral toxicity

تعداد نتایج: 363248  

ABSTRACT Introduction: Impaired wound healing is a major concern specially in diabetic patients due to unregulated chronic hyperglycemia which further may lead to ulcer, gangrene, and its complications, therefore the development of natural, nontoxic and effective agent is required. we carried out an acute and subacute oral toxicity study on the Cyperus Papyrus (CP) ash in Wistar albino rats. C...

Journal: :Journal of ethnopharmacology 1998
A Cáceres B López S González I Berger I Tada J Maki

Extracts were prepared from 13 native plants used for the treatment of protozoal infections. Activity against bacteria and fungi was demonstrated by dilution procedures; Trypanosoma cruzi was evaluated in vitro against epimastigote and trypomastigotes and in vivo against trypomastigotes. In active extracts, toxicity was evaluated by Artemia salina nauplii, oral acute toxicity (1-5 g/kg) and ora...

Journal: :Postgraduate Medical Journal 1991

Journal: :Particle and Fibre Toxicology 2010

Journal: :Journal of the American College of Toxicology 1993

Journal: :Indian Journal of Dermatology, Venereology, and Leprology 2014

2016
Thomas Luechtefeld Alexandra Maertens Daniel P. Russo Costanza Rovida Hao Zhu Thomas Hartung

The European Chemicals Agency, ECHA, made available a total of 13,832 oral toxicity studies for 8,568 substances up to December 2014. 75% of studies were from the retired OECD Test Guideline 401 (11% TG 420, 11% TG 423 and 1.5% TG 425). Concordance across guidelines, evaluated by comparing LD50 values ≥ 2000 or < 2000 mg/kg body weight from chemicals tested multiple times between different guid...

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