This new transdermal contraceptive system (contraceptive patch), Evra (Janssen-Cilag), received a UK product licence in 2003. In clinical trials: Consistent doses of norelgestromin and ethinyl oestradiol are released into the systemic circulation daily. Pharmacokinetic data suggest that levels are sufficient to inhibit ovulation for at least 7 days. The overall Pearl index for the contraceptive...

The side-effects encountered by 1,090 patients taking the oral contraceptive pill were reviewed. The main side-effects were migraine, headaches, weight gain, depression, and irregular bleeding. Reasons for changing the Pill are discussed, and recommendations are suggested for a way of monitoring patients taking the Pill. Analysis of the results show that 50 per cent of patients are happy with t...

We present two cases of female patients with a history of depression who developed depressive symptoms after treatment with hormonal contraceptives (HC) in the form of combined oral contraceptive pill, progestin-only pill and combined contraceptive vaginal ring. The presented two cases are based on the women's medical records complemented by personal interviews. The existing literature on the e...

1. Nailfold capillary pressure, digital blood flow and skin temperature have been measured on days 7, 14, 21 and 28 of the menstrual cycle in 10 women on a combined oral contraceptive pill and 10 control subjects with normal menstrual cycles. 2. Capillary pressure and digital blood flow were statistically significantly higher in the group taking an oral contraceptive pill compared with control ...

This was a comparative study of side effects and acceptability of low-dose pills administered by the oral and vaginal rout. In an experimental clinical trial study, undesirable side effects of nausea, dysmenorrhea, breast tenderness, gastrointestinal disorders, vertigo, headache, and breakthrough bleeding (BTB) were studied. The participants of the case and the control groups were the same wome...

Hormone-based therapies including combined oral contraceptive medications and spironolactone are considered effective therapies to treat adult acne in women. Our objective is to provide a concise and comprehensive overview of the types of hormonal therapy that are available to treat acne and comment on their efficacy and safety profiles for clinical practice. A systematic search using the PubMe...

OBJECTIVES To establish if advice concerning risks of pregnancy when taking oral contraceptive pill and antibiotics is being offered. METHOD A retrospective audit of notes of 100 female patients aged 15-39 who were prescribed antibiotics. RESULTS Documentation of use of contraception was noted in 3% of patients. Advice concerning risks and further precautions was noted in this 3% but not in...

The ?birth control pill,? more commonly known as ?the pill,? is a form of contraception [4] taken daily in pill form and consisting of synthetic hormones [5] formulated to prevent ovulation [6], fertilization [7], and implantation [8] of a fertilized egg [9]. The US Food and Drug Administration [10] (FDA) approved the first birth control [11] pill, Enovid [12], in June 1960. It was the first co...

CONTEXT Oral contraceptives are the most popular form of reversible contraception used in developed countries. Their efficacy depends on how consistently and correctly they are used. METHODS The incidence of inconsistent pill use was estimated from data from a random sample of 1,234 pill users who participated in a French population-based survey in 2000. Multivariate logistic regressions were...