BACKGROUND : In a pilot study of awake volunteers, intraocular pressure (IOP), choroid layer thickness, and optic nerve diameter were shown to increase in the prone position over 5 h with a nonsignificant trend of attenuation using a 4-degree increase of table inclination. These effects have previously not been isolated from anesthetic and fluid administration over a prolonged period, using an ...

purpose: to report a case of unilateral severe visual loss and bilateral optic disc cupping secondary to brain metastasis of bronchogenic carcinoma patient and findings: a 48 year-old woman presented with severe visual loss of left eye without redness or pain or any systemic findings .clinical findings included decreased visual acuity of left eye to 4 m cf and (+3) positive marcus-gunn reflex ....

OBJECTIVES This study investigated whether it is feasible to use sonography to monitor changes in the optic nerve sheath diameter in a porcine model. METHODS A fiber-optic intracranial pressure transducer was surgically placed through the frontal sinus directly into the brain parenchyma of adult Yorkshire pigs (n = 5). A second bolt was placed on the contralateral side for intraparenchymal fl...

Assessment of the peripapillary nerve fiber layer and macular thickness can be determined in ophthalmology using optical coherence tomography (OCT). Decreased nerve fiber layer thickness and macular ganglion cell thickness in optic nerve ischemia have been correlated with visual field loss. OCT allows deep optic nerve head evaluation which helps understand pathophysiology of diseases.  Furtherm...

STUDY OBJECTIVE We investigate the test performance of emergency physician-performed sonographic measurement of optic nerve sheath diameter for diagnosis of increased intracranial pressure. METHODS Children between the ages of 0 and 18 years with suspected increased intracranial pressure were prospectively recruited from the emergency department and ICU of an urban, tertiary-level, freestandi...

The ability of NGF (2.5S subunit) to support the survival of adult rat retinal ganglion cells (RGCs) and optic nerve fibers after intracranial section of the optic nerve was investigated. NGF was injected intraocularly at a dose of 3 micrograms/injection every 2.3 d from the day of axotomy to analysis. Control animals received cytochrome c injections. The survival of RGCs was analyzed in whole-...

introduction: elevated intracranial pressure (icp) is a major and potentially lethal disorder in patients admitted to the emergency department (ed). several methods are being used to investigate for elevated icp. here we assessed and compared the diagnostic accuracy of two existing tools of ophthalmoscopy and optic nerve ultrasonography in detection of elevated icp. methods: 131 participants wi...