The implementation of a developmental continuum for intelligence professionals, based on a traditional competency model may be ubiquitous across the breadth of intelligence. This paper argues that specialised contextual and cultural education and training and subsequent recognition of those skills, knowledge and attributes, is an essential element in achieving organisational and individual obje...

[1] Ozone profiles from the Microwave Limb Sounder (MLS) onboard the Aura satellite of the NASA’s Earth Observing System (EOS) were experimentally added to the European Centre for Medium-range Weather Forecasts (ECMWF) four-dimensional variational (4D-var) data assimilation system of version CY30R1, in which total ozone columns from Scanning Imaging Absorption Spectrometer for Atmospheric CHart...

Internet technologies bring with them a host of ramifications for the personal user, including a threat to personal privacy and anonymity. Anonymity and privacy are very closely integrated. Anonymity can be regarded as a way to protect one’s privacy. Third parties, providing Internet services, can record and collect user data in order to create user profiles. This is done in numerous ways, such...

Inorganic particulate matter in foods and drugs is discussed from the standpoint of determination by optical microscopy, source, and regulatory significance. Some particulate matter may be generated as extraneous material and traced to specific operational practices during processing and production with excessive levels associated with deficiencies in good manufacturing practices. Other particl...

The purpose of the POSTGRES project was to build a next generation DBMS to rectify the known deficiencies in current relational DBMSs. This system, constructed over a four year period by one full time programmer and 3-4 part time students is operational and consists of about 180,000 lines of C. POSTGRES is available free of charge and is being used by perhaps 125 sites around the world. This pa...

Research has overwhelmingly supported the proposition that safe injection facilities (SIFs) are successful in meeting their stated objectives. However, the methodological and analytic approaches used in these studies have not been scrutinized to any significant degree. Previous studies are compromised by an array of deficiencies, including a lack of baseline data, insufficient conceptual and op...

[This corrects the article on p. 102 in vol. 6, PMID: 25852744.].

Biological cells are extremely sensitive to temperature. What is the mechanism? We compute the thermal stabilities of the whole proteomes of Escherichia coli, yeast, and Caenorhabditis elegans using an analytical model and an extensive database of stabilities of individual proteins. Our results support the hypothesis that a cell's thermal sensitivities arise from the collective instability of i...

References: l)Nussbaum,R.L., Airhart,S.D. and Ledbetter.D.H. (1986) Am. J. Med. Genet. 23, 457-466. 2)Patterson,M.N., Bell,M.V., BloomfieldJ,, Flint,T., Dorkins.H., Thibodeau.S.N., Schaid,D., Bren,G., Schwartz,C.E., Wieringa,B., Ropers,H.-H., Callen.D.F., Sutherland.G., Froster-Iskenius.U., Vissing.H. and Davies,K.E. (1989) Genomics 4, 570-578. A Taql polymorphism adjacent to the factor VIII ge...

Abstract: Aging is associated with the accumulation of misfolded and damaged proteins. This accumulation is the result of an imbalance of proper protein folding, maintenance, and disposal. Maintaining proteostasis is critical to the health and life of an organism. While studies consistently observe that the proteostasis network diminishes with age, the effects on individual mechanisms have not ...