The afferent renal nerves enhance sympathetic activity in the one-kidney, one-clip hypertensive rat. We have also found adenosine-sensitive nerve endings in the renal pelvis that, when stimulated, increase sympathetic activity producing hypertension. To determine whether adenosine, which is excreted when renal blood flow is reduced, activates the afferent renal nerves in one-kidney, one-clip hy...

Objective(s) We investigated the effects of low-dose morphine on nitric oxide (NO) and angiogenesis in two-kidney one clip hypertensive (2K1C) rats. Materials and Methods Male rats were divided into two groups: sham-clip operated and 2K1C. Each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. Blood pressure, heart rate, plasma renin activity (PRA), NO concentration an...

objective(s) we investigated the effects of low-dose morphine on nitric oxide (no) and angiogenesis in two-kidney one clip hypertensive (2k1c) rats. materials and methods male rats were divided into two groups: sham-clip operated and 2k1c. each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. blood pressure, heart rate, plasma renin activity (pra), no concentration and m...