An endemic focus of onchocerciasis, the so-called “‘river blindness” widespread in parts of Africa, has been discovered in Brazil. Until recently the only confirmed foci ! in this Hemisphere were in Guatemala, Mexico, Colombia, and Venezuela. The research confirming this new Brazilian focus indicates the disease has spread over a fairly large swath of backlands in the vicinity of the Brazil-Ven...

background: this study was carried out in opi-agu a tropical semi-urban autonomous community comprising of three villages in enugu state, nigeria, between the months of april and june 2010. it was designed to determine the prevalence of onchocerca volvulus infection and assess the perception of the disease among the inhabitants of this community. methods: a total number of 305 individuals compr...

BACKGROUND Recently, several epidemiological studies performed in Onchocerca volvulus-endemic regions have suggested that onchocerciasis-associated epilepsy (OAE) may constitute an important but neglected public health problem in many countries where onchocerciasis is still endemic. MAIN TEXT On October 12-14th 2017, the first international workshop on onchocerciasis-associated epilepsy (OAE)...

Recent studies have shown that single-dose combination therapy with three currently approved antifilarial drugs (ivermectin, diethylcarbamazine (DEC), and albendazole, or IDA) is superior to current regimens used in lymphatic filariasis (LF) elimination programs. IDA may help to accelerate LF elimination in Africa, which has lagged behind other regions. Although it has not yet been tested, IDA ...

BACKGROUND Human onchocerciasis is a neglected tropical parasitic disease caused by Onchocerca volvulus (O. volvulus) that may result in devastating skin and eye morbidity. Even though the disease is targeted for elimination, there was little or no information on the level of onchocerciasis endemicity for implementation of community directed treatment with ivermectin (CDTI) in the current study...

INTERVENTION Few studies have documented the interruption of onchocerciasis and Lymphatic Filariasis (LF) by integrated chemotherapy in Uganda. The study describes the interruption of transmission of the two diseases co-endemic in Obongi focus, north western Uganda. Base line data for Onchocerciasis and LF were collected in 1994 and 2006, respectively. Annual mass drug administration for onchoc...

www.thelancet.com Vol 368 December 2, 2006 1947 those involved in neglected tropical diseases, and the private sector. After the review, the African Ministers of Health made the Yaoundé Declaration (panel). The declaration also welcomes the longstanding commitment of donors and NGDOs to onchocerciasis control and the pledge of Merck to provide ivermectin for as long as is needed. It also urged ...

Although onchocerciasis in cattle and horses in Japan had been noted in the veterinary field since the early 1950s, research on human onchocerciasis that is caused by Onchocerca volvulus was carried out only in the early 70s. It began when I did a brief study of skin test for onchocerciasis cases in Guatemala, Central America, in collaboration with Dr. H. Figueroa [1] using a Dirofilaria antige...

Onchocerciasis (river blindness) is a major public health problem in sub-Saharan Africa. Major disease-control programs have greatly reduced both disease and infection prevalence by mass distribution of donated ivermectin. Recent studies have shown that local elimination was achieved in some areas following many years of ivermectin. The global health community has recently decided to build on t...

THIS paper aims at describing, illustrating, and interpreting the ocular lesions associated with onchocerciasis. The literature of onchocerciasis already includes many pictures of the ocular lesions. The paintingst and diagrams in this paper supplement those previously published and are intended to fill gaps in the existing literature. The accompanying text expresses the author's views on the i...