نتایج جستجو برای: olfactory memory

تعداد نتایج: 280746  

2010
Florence Kermen Sébastien Sultan Joëlle Sacquet Nathalie Mandairon Anne Didier

BACKGROUND It has recently been proposed that adult-born neurons in the olfactory bulb, whose survival is modulated by learning, support long-term olfactory memory. However, the mechanism used to select which adult-born neurons following learning will participate in the long-term retention of olfactory information is unknown. We addressed this question by investigating the effect of bulbar cons...

Journal: :Biochemical and biophysical research communications 2008
Shixing Zhang Yan Yin Huimin Lu Aike Guo

Dopamine is necessary for the aversive olfactory associative memory formation in Drosophila, but its effect on other stages of memory is not known. Herein, we studied the effect of enhanced dopaminergic signaling on aversive olfactory memory retention in flies. We used l-3,4-dihydroxyphenylalanine (l-DOPA) to elevate dopamine levels: l-DOPA-treated flies exhibited a normal learning performance,...

2011
Holly LaFerriere Daniela Ostrowski Douglas J. Guarnieri Troy Zars

The genetic mechanisms that influence memory formation and sensitivity to the effects of ethanol on behavior in Drosophila have some common elements. So far, these have centered on the cAMP/PKA signaling pathway, synapsin and fas2-dependent processes, pumilio-dependent regulators of translation, and a few other genes. However, there are several genes that are important for one or the other beha...

2018
Grazyna Lietzau William Davidsson Claes-Göran Östenson Fausto Chiazza David Nathanson Hiranya Pintana Josefin Skogsberg Thomas Klein Thomas Nyström Vladimer Darsalia Cesare Patrone

Recent data suggest that olfactory deficits could represent an early marker and a pathogenic mechanism at the basis of cognitive decline in type 2 diabetes (T2D). However, research is needed to further characterize olfactory deficits in diabetes, their relation to cognitive decline and underlying mechanisms.The aim of this study was to determine whether T2D impairs odour detection, olfactory me...

Journal: :Neuron 2007
Xu Liu William C. Krause Ronald L. Davis

In both mammals and insects, neurons involved in learning are strongly modulated by the inhibitory neurotransmitter GABA. The GABAA receptor, resistance to dieldrin (Rdl), is highly expressed in the Drosophila mushroom bodies (MBs), a group of neurons playing essential roles in insect olfactory learning. Flies with increased or decreased expression of Rdl in the MBs were generated. Olfactory as...

2011
Holly LaFerriere Katherine Speichinger Astrid Stromhaug Troy Zars

Memory phases, dependent on different neural and molecular mechanisms, strongly influence memory performance. Our understanding, however, of how memory phases interact is far from complete. In Drosophila, aversive olfactory learning is thought to progress from short-term through long-term memory phases. Another memory phase termed anesthesia resistant memory, dependent on the radish gene, influ...

Journal: :Neuron 2004
Thomas Preat

Two dorsal paired medial (DPM) neurons express the Amnesiac neuropeptide and project onto mushroom bodies, the Drosophila olfactory memory center. In this issue of Neuron, Keene et al. show that higher-level brain circuits process various olfactory memories differently. DPM neurons are required during acquisition of some odors and during memory consolidation of others. These findings reveal a s...

Journal: :Learning & memory 2004
Daniel A Levy Ramona O Hopkins Larry R Squire

In humans, impaired recognition memory following lesions thought to be limited to the hippocampal region has been demonstrated for a wide variety of tasks. However, the importance of the human hippocampus for olfactory recognition memory has scarcely been explored. We evaluated the ability of memory-impaired patients with damage thought to be limited to the hippocampal region to recognize a lis...

Journal: :Chemical senses 1996
J P Royet H Paugam-Moisy C Rouby D Zighed N Nicoloyannis S Amghar G Sicard

Smelling an odour induces a pattern of sensations, images and memories which participate in identification. It was proposed that perceptual memory performances for odours could be inferred from the description of these olfactory representations. The subject was asked to elaborate an odour descriptor profile, and a short-term odour recognition memory task was chosen to test the individual percep...

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