In the 1960s and 1970s, there was widespread discussion in Japan about pathological experience of “unpleasant odors emanating from one's body.” This symptom is called “Jikoshu,” this term used combination with various words, such as “Genkaku” (hallucination) “Moso” (delusion), reflecting its symptomatological ambiguity. The best-known English-language literature Jikoshu-Kyofu (Jikoshu phobia). ...

Olfactory disorder takes a special place among non-motor symptoms of Parkinson's disease (PD) as one of earliest signs of the disease. Based on literature data, authors suggest that simple and structured tests for detection of olfactory disorders should be part of diagnostic algorithm for early detection of PD) and occupy a special place in differential diagnosis of diseases of the extrapyramid...

Kallmann syndrome (KS) is a neuronal migration disorder characterised by hypogonadotrophic hypogonadism and anosmia or hyposmia. Five patients with clinical findings suggestive of KS were evaluated with MRI. All patients had abnormalities of olfactory system. Olfactory bulbs were absent in all patients. Olfactory sulci were absent in 3 patients and hypoplastic in 2 patients. Anterior pituitary ...

Odor identification ability and detection threshold sensitivity were measured in 25 probands with Huntington's disease, 12 at-risk offspring, and 37 unrelated controls. Relative to controls and at-risk offspring, HD patients exhibited significant impairment on both measures of olfactory function. By contrast, at-risk offspring did not evidence any olfactory impairment relative to controls. Thus...

Olfactory disorders are one of the characteristic symptoms coronavirus disease 2019 (COVID-19), which causes infection and inflammation upper lower respiratory tract. To our knowledge, there no treatments for COVID-19-related olfactory disorder. Here, we report five disorder cases in COVID-19, treated using Japanese traditional (Kampo) medicine, kakkontokasenkyushin’i. We patients with mild COV...

Objective: The authors examined the relationship between deficits in olfactory identification and duration of illness in young and elderly patients with schizophrenia. Method: Olfactory identification performance of 38 patients with schizophrenia and 40 normal subjects was compared by using the University of Pennsylvania Smell Identification Test. Results: The schizophrenic patients demonstrate...

BACKGROUND Post-traumatic olfactory dysfunction is common but has a poor prognosis. The purpose of this study was to analyze the effect of clinical features on improvements in post-traumatic olfactory dysfunction. METHODS From 2007 to 2013, patients with post-traumatic olfactory dysfunction were enrolled. Olfactory function was assessed using the Sniffin' Sticks test at the first and final vi...

OBJECTIVE The authors' goal in this study was to compare the size of olfactory bulbs of patients with schizophrenia and those of healthy subjects. METHOD Magnetic resonance imaging scans of olfactory bulbs were obtained from 26 patients with schizophrenia and 22 healthy comparison subjects. A reliable region of interest procedure was used to measure olfactory bulb volume. RESULTS Patients e...