Endohedral metallofullerenol Gd@C(82)(OH)(22) has recently been shown to effectively inhibit tumor growth; however, its potential adverse bioeffects remain to be understood before its wider applications. Here, we present our study on the interaction between Gd@C(82)(OH)(22) and WW domain, a representative protein domain involved in signaling and regulatory pathway, using all-atom explicit solve...

The formation of Spemann organizer is one of the most important steps in dorsoventral axis determination in vertebrate development. However, whether the organizer forms autonomously or is induced non-cell-autonomously is controversial. In this report we have isolated a novel zebrafish homeobox gene, dharma, capable of inducing the organizer ectopically. The expression of dharma was first detect...

background to estimate oral hygiene (oh) status in the iranian population in 2011, and to determine the influence of socio-economic characteristics on oh, and its interrelation with common risk factors of non-communicable diseases (ncds).   methods data including a total of 12,105 individuals aged 6-70 years were obtained from the sixth round of the surveys of ncds risk factors in iran. oh was ...

   Adsorption of OH on the PdxCu3-x(x=0-3) small clusters is investigated by density functional theory calculations. It is found that OH adsorbs in three possible modes including on top, bridge and hollow sites while the structures where OH bridges between two atoms are the most stable structures. The Pd-Pd, Pd-Cu and Cu-Cu equilibrium distances for most of the systems...

background: vitamin d deficiency is a pandemic problem mostly diagnosed in elderly. few studies are available exclusively done on the topic among young adults. specific professions such as medical students may have higher risk for developing hypovitaminosis d. we aimed to assess the vitamin d status in medical students of iran university of medical sciences; and to define a cut‑off point for 25...

Vitamin D (VIT D) deficiency is determined by serum 25-OH-D. Several studies revealed high prevalence of VIT D deficiency in females of the Asian sunny countries. 162 females referred to Urmia Orthopedic Clinics, with bone and muscle pain with the ages 15 up to 40 yrs participated in the study. The individuals were not pregnant, lactating, with no systemic or neurological diseases during the co...