Concentrations of oestrogens in the blood plasma and seminal plasma of mature boars are high. However, little is known about their concentrations after reaching sexual maturity. The aim of this study was to determine the concentration of oestrogens in blood plasma and seminal plasma of boars during the postpuberal period. Free and conjugated oestrone and oestradiol-17beta were determined by rad...

BACKGROUND Recurrent urinary tract infection (RUTI) is defined as three episodes of urinary tract infection (UTI) in the previous 12 months or two episodes in the last six months. The main factors associated with RUTI in postmenopausal women are vesical prolapse, cystocoele, post-voidal residue and urinary incontinence, all associated with a decrease in oestrogen. The use of oestrogens to preve...

Introduction Oestrogens play an important role in the development of breast cancer. Oestrone sulphate is a major source of active oestrogens in the breast, being converted to oestrone by oestrone sulphatase. Oestrone is then converted to oestradiol, a potent oestrogen strongly implicated in the development of breast cancer, by the enzyme 1713-hydroxysteroiddehydrogenase. In vitro oestrone sulph...

A grazing experiment was carried out to study the concentration of phyto-oestrogens in herbage for cattle and in milk during two periods (May and June). Forty-eight Danish Holstein cows were divided into four groups with four treatment diets; white clover, red clover, lucerne and chicory-rich pastures. Each experimental period lasted 15 days. Herbage samples from the first day and individual mi...

The value of oestrogens in the treatment of osteoporosis has been shown by two main types of evidence. Firstly, increased calcium retention, due to a reduction in both faecal and urinary excretion, has been shown by metabolic balance studies (Reifenstein and Albright 1947). Secondly, the progress of the disease, as judged by height loss and bone density, is arrested (Henneman and Wallach 1957),...

The treatment of prostatic carcinoma, the second commonest carcinoma in the Western world, remains controversial although opinion has leaned towards oestrogens rather than orchiectomy unless the patient suffers a thrombo-embolic tendency.9-10 We report here a retrospective study of two statistically comparable groups of patients: one treated with oestrogens (Stilboestro!) the other by orchiectomy.

In many species of oviparous reptiles, the first steps of gonadal sex differentiation depend on the incubation temperature of the eggs. Feminization of gonads by exogenous oestrogens at a male-producing temperature and masculinization of gonads by antioestrogens and aromatase inhibitors at a female-producing temperature have irrefutably demonstrated the involvement of oestrogens in ovarian diff...

which Dr Coope and her colleagues based their statistics are not available and may, in fact, not differ markedly from the range of normal for their laboratory. For example, although they comment on raised levels of factor X, there is no significant difference in this parameter between their oestrogentreated and placebo groups. The thromboelastogram also showed no significant change. The clinica...

CONTEXT Oestrogens were proven effective in the hormonal treatment of advanced prostate cancer (PCa) >60 yr ago and are still used as second-line hormonal therapy. Paradoxically, oestrogens might also be involved in the development and progression of PCa. OBJECTIVE To examine mechanisms of how oestrogens may affect prostate carcinogenesis and tumour progression. EVIDENCE ACQUISITION Recent ...