Tooth morphogenesis is carried out by a series of reciprocal interactions between the epithelium and mesenchyme in embryonic germs. Previously clonal dental epithelial cell (epithelium of molar tooth germ (emtg)) lines were established from an embryonic germ. They were odontogenic when combined with a dental mesenchymal tissue, although the odontogenesis was quantitatively imperfect. To improve...

The influence of diet and fluoride on odontogenesis in rats was investigated. 20 foetuses, 20 days old, were divided into four groups. The control group was fed with the standard diet and drank water with 0.16 mg F/l. The second, third and fourth groups were fed with the deficit, experimental diet and drank distilled water with 10 and 110 mg of natrium fluoride per litre or without fluoride. In...

Granulin epithelin precursor (GEP) is a new growth factor that functions in brain development, chondrogenesis, tissue regeneration, tumorigenesis, and inflammation. The goal of this study was to study whether GEP was critical for odontogenesis and amelogenesis both in vivo and in vitro. The in situ hybridization and immunohistochemistry data showed that GEP was expressed in both odontoblast and...

Gene expression controls the cellular differentiation and morphogenesis for body organisation. Every species has different unique patterns this is influenced by certain group of genes called as homeobox genes. Molecular events are involved in tooth development process or odontogenesis also controlled It was first identified fruit fly Drosophila Melanogaster.

Abnormalities of tooth shape and size generally coexist, as both are determined during the morphodifferentiation stage of odontogenesis. This report describes a case of lobodontia exhibiting multiple dental anomalies of which, "fang like" cuspids, multituberculism of molars, hypodontia along with severe generalized microdontia are distinctive. Radiographic features, diagnostic convolutions, dif...

The word “odontodysplasia” was coined by Zegarelli, et al. (1963). Because this abnormality has a tendency to affect only one quadrant, “regional odontodysplasia” became the most accepted term to define it. The same condition has been described under other denominations, such as “odontogenic dysplasia, “localized arrested tooth development” “ghost teeth, “odontogenesis imperfecta”, “unilateral ...