Neurolathyrism is a unique neurodegeneration disease caused by β-N-oxalyl-L-α, β- diaminopropionic (β-ODAP) present in grass pea seed (Lathyrus stativus L.) and its pathogenetic mechanism is unclear. This issue has become a critical restriction to take full advantage of drought-tolerant grass pea as an elite germplasm resource under climate change. We found that, in a human glioma cell line, β-...

Epidemics of lathyrism, a neurological syndrome of spastic paraparesis, have occurred during severe droughts in Europe, Asia, and Africa for millenia. Causation is linked to exposure to β-N-oxalyl-L-α,β-diaminopropionic acid (β-L-ODAP), a neurotoxin in Lathyrus sativus. Lathyrism shares neurological features with konzo, a syndrome of predominantly spastic paraparesis which occurs during drought...

the nutritive value of grass pea (lathyrus sativus l.) hay was evaluated based on its chemical composition, gas production, fractioning of protein in cncps and afrc systems, metabolizable energy (me), rumen degradability through in situ technique and in vitro digestibility through tilley and terry method. the crude protein (cp), neutral detergent fiber (ndf) and acid detergent fiber (adf) value...

This study was performed to investigate how smoke solution affects dry matter loss, crude protein (CP) and toxic compound ODAP contents of grass pea in hydroponic media during seven days period. Three doses solutions (1, 5 10%, V: V) by diluting with tap water were applied seeds as priming agent, used a control (0%). The experiment arranged according the split-plot design three replications. Co...

Introduction In Tunisia the genus Lathyrus is represented by 15 native species , distributed essentially in marginal environments in the north of the country. Many of them are of considerable agronomic interest as forage (L. ochrus and L. articulatus) and as human food (L. cicera and L. sativus). These species are under utilised and in the past little effort has been made to expand the selectio...