background: mucous membrane pemphigoid (mmp) is considered an autoimmune blistering disease that  predominantly affects mucous membranes. various treatments are available for controlling the diseases, but not all of them may respond. objective: in this review, the data on seventy patients with mmp who were under treatment of intravenous immunoglobulin (ivig) are categorized and then analyzed. t...

background: methotrexate has an important role in treatment of acute leukemia. we measured methotrexate level in csf and blood of children with acute lymphoblastic leukemia to determine complications and outcomes. materials and methods: one hundred and twenty patients (73 male, 47 female), with mean age at diagnosis of 6.1 years (11mo_15years) entered the study. patients were divided into two g...

Ocular surface disease (OSD), a disorder affecting the lacrimal and meibomian glands corneal conjunctival epithelium, is well-known complication of topical glaucoma therapy. OSD can present as new or pre-existing condition that virtually any anti-glaucoma formulation exacerbate. As such, both frequently coexist. Typical symptoms include ocular discomfort, redness, burning, dryness, whereas sign...

BACKGROUND AND PURPOSE Topiramate (TPM) is a sulfa-derivative monosaccharide that is used mainly for treating epilepsy and preventing migraine. Within the gamut of side effects attributable to this drug, ophthalmologic manifestations are of crucial importance. In this study, for the first time, the aim was to provide a systematic literature review regarding this issue. METHODS For the time pe...

oral contraceptive pills have several side effects especially on the gastrointestinal tract and liver. absorption of low dose (ld) pills by the vaginal route avoids the first pass of the steroids through these tracts and probably has fewer side effects. this study was a cohort study for evaluation of side effects and acceptability of ld pills administered by the vaginal route. in a clinical tri...

Purpose To present a previously unreported retinal side-effect from topiramate use in two cases. Observations Macular neurosensory retinal detachments were seen in two patients shortly after beginning oral topiramate. The macular detachments resolved shortly after discontinuing this medication. Conclusions and importance As these two cases represent the first reports of topiramate-induced m...

how to cite this article: talebian a, goudarzi rm, mohammadzadeh m , mirzadeh as. vincristine-induced cranial neuropathy. iran j child neurol. 2014 winter; 8(1):66-68.   abstract vincristine (vcr) is a vinca alkaloid that is used for treatment of many malignancies. the vinca alkaloids are neurotoxic, usually causing a peripheral neuropathy, but cranial neuropathies are rare as side effects.  de...

remifentanil is an ultra short acting opioid that is suitable for many operations and is wildly used for induction and maintenance of anesthesia. in this article we have reported the incidence of abdominal pain after cataract surgery in patients with remifentanil based anesthesia. this study is a randomized single blind clinical trial on 300 patients who were candidates for elective cataract su...

Introduction: In this study, we studied ocular morbidity among smokers in central India, awareness regarding ocular side effect among smoker and effect of awareness about smoking among smokers. Study was conducted with aim: To study effect of smoking on tear film among smokers in Central India, To study awareness regarding health related problems effect among smokers, To study effect of awarene...