نتایج جستجو برای: octanoate
تعداد نتایج: 540 فیلتر نتایج به سال:
Using pieces of rat pancreas incubated bation medium to 3.0 mg./ml. without in Krebs-bicarbonate buffer containing addition of octanoate produced a slight0.6 mg. glucose/ml., it has been found ly smaller though significant (p < .05) that addition of 3.0 mM. octanoate to increase in insulin release (2.96 t 0.96 the incubation medium significantly (p &J./mg.) above control levels. In con< .OOl) i...
Amino acid oxidation was studied in perfused hearts and incubated hemidiaphragms of rats fed ad Zibitum. Hearts were perfused with Krebs-Henseleit bicarbonate buffer containing glucose and 0.1 mu amino acids. The addition of 1 mM octanoate to the medium markedly stimulated 14COz production from [1-r4C}leucine, isoleucine, and valine; inhibited r4C02 production from [lJ4C]alanine, pyruvate, and ...
The binding of hexanoic, octanoic, and decanoic acids to defatted human plasma albumin was measured by equilibrium dialysis at 37” in a calcium-free Krebs-Ringer phosphate buffer, pH 7.4. The results were analyzed in terms of multiple stepwise equilibria. For each of the albumin binding sites, the magnitude of the equilibrium constants increased as the chain length of the acid increased: decano...
BACKGROUND Octanoate is a medium-chain fatty acid (MCFA) that is rich in milk and tropical dietary lipids. It also accounts for 70% of the fatty acids in commercial medium chain triglycerides (MCT). Use of MCT for weight control tracks back to early 1950s and is highlighted by recent clinical trials. The molecular mechanisms of the weight reduction effect remain not completely understood. The f...
In studies designed to measure rates of hepatic cholesterogenesis, rat liver slices were incubated with [Wlacetate in the presence of unlabeled octanoate and with [l*C]octanoate in the presence of unlabeled acetate to assess the degree of intracellular dilution and compartmentalization of the acetyl-CoA pools. It was observed that when increasing concentrations of [14C]acetate were used, the in...
Long-acting Neuraminidase Inhibitor Laninamivir Octanoate as Post-exposure Prophylaxis for Influenza
BACKGROUND A single administration of laninamivir octanoate, a long-acting neuraminidase inhibitor, has been proven to be effective in the treatment of influenza but not for post-exposure prophylaxis. METHODS We conducted a double-blind, multicenter, randomized, placebo-controlled study to determine if a single administration of laninamivir octanoate 40 mg was superior to placebo for post-exp...
This work examines the effects of six pesticides on five green algae: Pseudokirchneriella subcapitata, Scenedesmus quadricauda, Scenedesmus obliquus, Chlorella vulgaris and Chlorella pyrenoidosa. The results indicate that the decreasing order of the average toxicity to five algae was: fluazinam > propineb > maneb > mancozeb > zineb > bromoxynil octanoate. however, according to sensitivity magni...
Wax esters are long-chain esters that have been widely applied in premium lubricants, parting agents, antifoaming agents and cosmetics. In this study, the biocatalytic preparation of a specific wax ester, cetyl octanoate, is performed in n-hexane using two commercial immobilized lipases, i.e., Lipozyme(®) RMIM (Rhizomucor miehei) and Novozym(®) 435 (Candida antarctica). Response surface methodo...
The profile of organic acids in plasma of patients with a deficiency of medium-chain acyl-CoA dehydrogenase (EC 1.3.99.3) was determined by gas-liquid chromatography of trimethylsilylated derivatives of the acids isolated by ethyl acetate extraction. All 13 patients had increased concentrations of free octanoate, cis-4-decenoate, and decanoate in their plasma. Cis-4-decenoate, an intermediary m...
Pseudomonas resinovorans produced poly-beta-hydroxyalkanoates (PHAs) when grown on hydrocarbons but not on glucose. In a chemostat culture, the PHA composition was beta-hydroxybutyrate (C4)-beta-hydroxyhexanoate (C6)-beta-hydroxyoctanoate (C8)-beta-hydroxydecanoate (C10) (1:15:75:9) on octanoate and C4-C6-C8-C10 (8:62:23:7) on hexanoic acid. Contrary to the reported behavior of Pseudomonas oleo...
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