Methanolic extracts of Pterocarpus marsupium Roxb (P. marsupium) and Ocimum sanctum Linn (O. sanctum) were prepared separately and then administered to both non-diabetic and alloxan induced diabetic adult female Wistar rats as a mixture of both at a dosage of 500mg/kg body weight, and its effect was checked on serum and tissue lipids together with corticosterone, estrogen and progesterone profi...

The present investigation was conducted to determine the effect of PBZ and ABA on total phenol contents in different parts of Ocimum sanctum. Paclobutrazol (PBZ) a triazole fungicide, having plant growth regulator (PGR) properties, is reported to inhibit gibberellic acid biosynthesis and increase in abscisic acid and cytokinin contents. So, it necessitates the need to investigate the efficacy o...

Diabetes is a group of metabolic disease and associated with impaired glucose metabolism, resulting from defect in insulin secretion, action and both. The present study was undertaken to evaluate the insulin secretion and anti-oxidative potential of Ocimum sanctum extract in diabetic rats. The results showed that extensive oxidative stress is generated in tissues of diabetic rats, increased the...

The objective of this study was to investigate the anthelmintic efficacy of herbal drug (Ocimum sanctum) in Syphacia muris infected mice. The drugs were administrated to the infected mice on 18 , th 19 and 20 post infection days. The % efficacy due to test drug was observed on larva and adult worm th th recovery response. Larval and Adult worm recovery were found to be directly proportional to ...

AIM To evaluate the essential oil extract of the au Ocimum sanctum for its antibacterial and anti inflammatory efficacy. METHODS The essential oil extract was prepared in the Clevenger's apparatus. Antibacterial efficacy was tested against Enterococcus faecalis at two concentrations i.e. 100 & 50%. Bacterial growth was measured spectrophotometrically and percentage inhibition was calculated. ...

The present study was aimed to study the acute and subacute toxicity studies with orally administered 50% ethanolic leaves extract of Ocimum sanctum Linn (OSE). In acute toxicity tests, four groups of mice (n = 6/group/sex) were orally treated with doses of 200, 600, and 2000 mg/kg, and general behavior, adverse effects, and mortality were recorded for up to 14 days. In subacute toxicity study,...

The present study was designed to investigate the ameliorative potential of Ocimum sanctum and its saponin rich fraction in vincristine-induced peripheral neuropathic pain in rats. Peripheral neuropathy was induced in rats by administration of vincristine sulfate (50 mug/kg i.p.) for 10 consecutive days. The mechanical hyperalgesia, cold allodynia, paw heat hyperalgesia and cold tail hyperalges...

Plants have been used for the treatment of various diseases for thousands of years. Plants and plant-products are good sources of medications and provide raw materials for modern pharmaceuticals used for various ailments. Ocimum sanctum and Ocimum gratissimumis known to be an important medicinal plants from the ancient period in India. Thisstudy was carried out to investigate the phytochemical ...

BACKGROUND Nanotechnology is now regarded as a distinct field of research in modern science and technology with multifaceted areas including biomedical applications. Among the various approaches currently available for the generation of metallic nanoparticles, biogenic synthesis is of increasing demand for the purpose of green nanotechnology. Among various natural sources, plant materials are t...

Burns remain a major public health problem all over the world, especially in developing countries. Pseudomonas aeruginosa is a major cause of infection and a contributing factor in the death of patients with burns. So, there is a growing need to develop drugs which will prevent infections and complications more effectively than the presently used drugs. Ocimum sanctum L. (Holy basil in English ...