نتایج جستجو برای: nsm method

تعداد نتایج: 1630598  

2016
Yukari ISHIHARA Chieko SHIODA Norasuthi BANGPHOOMI Keita SUGIURA Kohei SAEKI Shumpei TSUDA Tatsuya IWANAGA Akiko TAKENAKA-UEMA Kentaro KATO Shin MURAKAMI Kazuyuki UCHIDA Hiroomi AKASHI Taisuke HORIMOTO

The biological function of a nonstructural protein, NSm, of Akabane virus (AKAV) is unknown. In this study, we generated a series of NSm deletion mutant viruses by reverse genetics and compared their phenotypes. The mutant in which the NSm coding region was almost completely deleted could not be rescued, suggesting that NSm plays a role in virus replication. We next generated mutant viruses pos...

2014
Pratibha Singh Shantinath S. Indi Handanahal S. Savithri

Groundnut Bud Necrosis Virus (GBNV) is a tripartite ambisense RNA plant virus that belongs to serogroup IV of Tospovirus genus. Non-Structural protein-m (NSm), which functions as movement protein in tospoviruses, is encoded by the M RNA. In this communication, we demonstrate that despite the absence of any putative transmembrane domain, GBNV NSm associates with membranes when expressed in E. co...

2017
Lena Collenburg Niklas Beyersdorf Teresa Wiese Christoph Arenz Essa M. Saied Katrin Anne Becker-Flegler Sibylle Schneider-Schaulies Elita Avota

Breakdown of sphingomyelin as catalyzed by the activity of sphingomyelinases profoundly affects biophysical properties of cellular membranes which is particularly important with regard to compartmentalization of surface receptors and their signaling relay. As it is activated both upon TCR ligation and co-stimulation in a spatiotemporally controlled manner, the neutral sphingomyelinase (NSM) has...

Journal: :Head & neck 2013
Rafaela Elvira Rozza-de-Menezes Raquel Machado Andrade Mônica Simões Israel Karin Soares Gonçalves Cunha

BACKGROUND Oral nerve sheath myxoma (NSM) is an uncommon benign neoplasm with Schwann-cell origin, which is frequently mistaken for neurothekeoma. We report a case of NSM on the buccal mucosa in a 42-year-old woman. This case is compared with previously reported cases and a systematic review is performed. METHODS AND RESULTS We conducted a case report and systematic review of oral cases consi...

2003
Shaofeng Yang Zeyad Ali Houssain Kettani Vinti Verma Qutaibah M. Malluhi

This paper presents the Network Storage Manager (NSM) developed in the Distributed Computing Laboratory at Jackson State University. NSM is designed as a Java-based, high-performance, distributed storage system, which can be utilized in the Grid environment. NSM architecture presents a framework offering parallelism, scalability, crash recovery, and portability for data-intensive distributed ap...

Journal: :Pakistan journal of biological sciences : PJBS 2010
Aydin Ozluk

The purpose of this study is to examine the effects of neurosecretory material (NSM) in Corpus Allatum (CA) of endoparasitic Pimpla turionellae L. on reproduction. For this purpose, the egg maturation of the insect and the amount of the NSM in CA of the serial section of the brain were studied. Egg maturation was determined by measuring the terminal oocyte length. In order to determine the amou...

Journal: :Breast 2016
Lorenzo Orzalesi Donato Casella Caterina Santi Lorenzo Cecconi Roberto Murgo Stefano Rinaldi Lea Regolo Claudio Amanti Manuela Roncella Margherita Serra Graziano Meneghini Massimiliano Bortolini Vittorio Altomare Carlo Cabula Francesca Catalano Alfredo Cirilli Francesco Caruso Maria Grazia Lazzaretti Luigi Cataliotti Marco Bernini

BACKGROUND Nipple sparing mastectomy is deemed surgically and oncologically safe based on a long lasting literature data from reviews of single institution series. This study aims at evaluating surgical and oncological outcomes of NSM on a large multi-institutional scale, by means of the Italian National registry. METHODS In July 2011 a panel of Italian specialists agreed upon and designed a ...

2013
Giovanni Almanzar Gernot Eberle Andrea Lassacher Christian Specht Christian Koppelstaetter Peter Heinz-Erian Rudolf Trawöger David Bernhard Martina Prelog

BACKGROUND Significant immunomodulatory effects have been described as result of cigarette smoking in adults and pregnant women. However, the effect of cigarette smoking during pregnancy on the lymphocyte subpopulations in newborns has been discussed, controversially. METHODS In a prospective birth cohort, we analyzed the peripheral lymphocyte subpopulations of smoking (SM) and non-smoking mo...

2016
Zhike Feng Fan Xue Min Xu Xiaojiao Chen Wenyang Zhao Maria J. Garcia-Murria Ismael Mingarro Yong Liu Ying Huang Lei Jiang Min Zhu Xiaorong Tao Aiming Wang

Plant viruses move through plasmodesmata to infect new cells. The plant endoplasmic reticulum (ER) is interconnected among cells via the ER desmotubule in the plasmodesma across the cell wall, forming a continuous ER network throughout the entire plant. This ER continuity is unique to plants and has been postulated to serve as a platform for the intercellular trafficking of macromolecules. In t...

Journal: :Open forum infectious diseases 2016
Bridget E Barber Timothy William Matthew J Grigg Uma Parameswaran Kim A Piera Tsin W Yeo Nicholas M Anstey

Background.  Endothelial nitric oxide (NO) bioavailability is impaired in severe falciparum malaria (SM). Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase (NOS), contributes to endothelial dysfunction and is associated with mortality in adults with falciparum malaria. However, factors associated with ADMA in malaria, including the NOS-substrate l-arginine, hemolysis, a...

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