GATA-type transcription factors (TFs) such as the nitrogen regulators AreA and AreB, or the light-responsive TFs WC-1 and WC-2, play global roles in fungal growth and development. The conserved GATA TF NsdD is known as an activator of sexual development and key repressor of conidiation in Aspergillus nidulans, and as light-regulated repressor of macroconidia formation in Botrytis cinerea. In th...

BACKGROUND Same-day discharge (SDD) after elective percutaneous coronary intervention is safe, less costly, and preferred by patients, but it is usually performed in low-risk patients, if at all. To increase the appropriate use of SDD in more complex patients, we implemented a "patient-centered" protocol based on risk of complications at Barnes-Jewish Hospital. METHODS AND RESULTS Our objecti...

Silicone rubber insulators are replacing the conventional ceramic and porcelain insulators rapidly in power transmission and distribution industry. Very limited field knowledge is available about the performance of silicone rubber insulators in polluted and contaminated environments and therefore need further investigation. A comprehensive analysis of silicone rubber sheets (intended for coatin...

Here we have characterized the putative Zn(II)2Cys6 transcription factor RosA from the filamentous fungus Aspergillus nidulans. The rosA gene encodes a protein of 713 aa, which shares 38% sequence similarity to Pro1 from Sordaria macrospora. In contrast to Pro1, which promotes the transition from protoperithecia to perithecia, RosA is a negative regulator of sexual development in A. nidulans. T...