N atriuretic peptides (NPs) include atrial NP (ANP), B-type NP, and C-type NP. NPs exert cardiovascular protective effects through interaction with their receptors. There are 2 major classes of NP receptors (NPRs): guanylyl cyclase–cou-pled receptors A and B (NPR-A and NPR-B) and inhibitory guanine nucleotide regulatory protein (inhibitory G protein)– coupled receptor C (NPR-C; Figure). The car...

Negative Poisson's ratio (NPR) materials have drawn significant interest because the enhanced toughness, shear resistance, and vibration absorption that typically are seen in auxetic materials may enable a range of novel applications. In this work, we report that single-layer graphene exhibits an intrinsic NPR, which is robust and independent of its size and temperature. The NPR arises due to t...

The effects of nitroglycerin (NTG) and nitroprusside (NPR) were examined in conscious dogs on measurements of left circumflex coronary blood flow and coronary diameter and on calculations of late diastolic coronary resistance (LDCR) and left circumflex coronary internal cross-sectional area (CSA). The effects of infusions of NTG, 8 microgram/kg/Min for 7 minutes, and NPR, 2.5 microgram/kg/min f...

INTRODUCTION The present study was conducted to establish the positive predictive value of congenital cardiac malformation diagnoses registered in the Danish National Patient Registry (NPR), thereby exploring whether the NPR can serve as a valid tool for epidemiologic studies of congenital cardiac malformations. MATERIALS AND METHODS The study population comprised every individual born from 2...

This paper proposes the necessity of developing a theory of psychology within non-photorealistic rendering (NPR). Despite the inherent flexibility of NPR within a variety of visual media, the psychological functionality of NPR remains largely unexplored. As such, we consider aspects of NPR in terms of general, biological, social, and environmental psychology paradigms using results from recent ...

Recently, various non-photorealistic rendering (NPR) techniques have been developed for computers to generate images of different artistic styles automatically. Due to the complexity of the algorithms, however, most NPR methods are limited to the processing of still images. It is the objective of this paper to extend and improve existing NPR techniques to enable near realtime processing of vide...

Negative lymph node counts has recently attracted attention as a prognostic indicator in colorectal cancer (CRC). But little is known about prognostic significance of negative to positive lymph node ratio (NPR) in CRC. Our aim was to determine impact of NPR on oncological outcomes in patients with stage III CRC. This retrospective study included 2,256 patients with stage III CRC under curative ...

The emergence of non-photorealistic rendering (NPR) over the greater part of a decade has created an intriguing new field espousing expression, abstraction and stylisation in preference to the traditional computer graphics concerns for photorealism. By lifting the burden of realism, NPR is capable of engaging with users, providing compelling and unique experiences through devices such as abstra...

RATIONALE C2238 atrial natriuretic peptide (ANP) minor allele (substitution of thymidine with cytosine in position 2238) associates with increased risk of cardiovascular events. OBJECTIVE We investigated the mechanisms underlying the vascular effects of C2238-αANP. METHODS AND RESULTS In vitro, human umbilical vein endothelial cell were exposed to either wild-type (T2238)- or mutant (C2238)...

Developing functional small-diameter vascular grafts is an important objective in tissue engineering research. In this study, we address the problem of compliance mismatch by designing and developing a 3D tubular construct that has a negative Poisson's ratio νxy (NPR). NPR constructs have the unique ability to expand transversely when pulled axially, thereby resulting in a highly-compliant tubu...