Chlamydia trachomatis is an obligate intracellular bacterium that exhibits a unique biphasic developmental cycle that can be disrupted by growth in the presence of IFN-γ and β-lactams, giving rise to an abnormal growth state termed persistence. Here we have examined the expression of a family of non-coding RNAs (ncRNAs) that are differentially expressed during the developmental cycle and the in...

vhs1 is a herpes simplex virus type 1 mutant defective in the shutoff of both host and alpha polypeptide synthesis. In cycloheximide reversal experiments, alpha mRNAs were significantly more stable in vhs1-infected cells than in cells infected with wild-type virus, whether assayed by in vitro translation or Northern blotting.

INTRODUCTION The residents of many Australian rural and remote communities do not have the essential infrastructure and services required to support healthy living conditions and community members choosing healthy lifestyle options. Improving these social determinants of health is seen to offer real opportunities to improve health among such disadvantaged populations. In this paper, we describe...

The study, commissioned by the Australian Nursing Council Inc. (ANCI), sought to develop an approach to the maintenance of continuing competence in nursing broadly acceptable to nurses in all States and Territories and included the conduct of a postal survey of registered nurses (RNs) throughout Australia. An options booklet and accompanying questionnaire were posted to a random sample of 2 % o...

The administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome. However, the prevalence of CLI-resistant Streptococcus pyogenes strains is increasing worldwide, and the effect of CLI on CLI-resistant S. pyogenes strains remains unknown. We aimed to evaluate the effect of CLI on the in vitro production of three major...

In early April 1998, the Centre for Disease Control in Darwin was notified of a possible case of dengue which appeared to have been acquired in the Northern Territory. Because dengue is not endemic to the Northern Territory, locally acquired infection has significant public health implications, particularly for vector identification and control to limit the spread of infection. Dengue IgM serol...

There is no morphological identification key to satisfactorily distinguish between the larvae of Aedes (Stegomyia) species with special consideration to endemic and exotic species in Australia. Difficulty in differentiation between exotic Aedes (Stegomyia) albopictus (Skuse) and Aedes (Stegomyia) scutellaris Walker has been described previously. Aedes (Stegomyia) larvae were collected during an...