Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumption. Valid biomarkers of flavonoid intake may be useful for estimating exposure in a range of settings. However, to date, few useful flavonoid biomarkers have been identified. In this study, we used ...

BACKGROUND Dark chocolate derived from the plant (Theobroma cacao) is a rich source of flavonoids. Cardioprotective effects including antioxidant properties, inhibition of platelet activity, and activation of endothelial nitric oxide synthase have been ascribed to the cocoa flavonoids. OBJECTIVE To investigate the effects of flavonoid-rich dark chocolate on endothelial function, measures of o...

Bryophytes are the second largest group in the plant kingdom, but studies conducted to better understand their chemical composition are limited and scattered. Axenically grown bryophytes expressed potential in biotechnological processes. The present study was designed to investigate the in vitro cell growth, culture parameters and their effect on flavonoid synthesis. Chlorophyll-containing call...

The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is one of the bioactive substances contributing to its medical applications. Among foodstuffs XN is found primarily in beer and its natural occurrence is surveyed. In recent years, XN has received much attention for its...

Citrus fruits contain two groups of flavonoid glycosides that have either rutinose (L-rhamnopyranosyl-ct-1,6-glucopyranoside) or neohesperidose (L-rhamnopyranosyl-:-1.2glucopyranosiele) as their saccharide components. Flavonoid rutinosides such as hesperidin. from mandarin oranges, are tasteless, and on the other hand, flavonoid neohesperidosides such as neohesperidin and naringin, from grapefr...

With an effort to investigate possible relationship between flavonoids and health, an accurate estimation of flavonoid intake is valuable. We estimated dietary flavonoid intake and identified the major food sources. Subjects were healthy adults aged >=19 y (n=11,474) who completed the 24-h dietary recall of the Korean National Health and Nutritional Examination Survey (2010-2012). The US Depart...

OBJECTIVE Flavonoids are phytochemicals with potentially beneficial biological effects that are poorly characterised in existing tables of food composition. DESIGN To describe new techniques for analysis, absorption, informatics and dietary assessment that are important in measuring the flavonoid content in foods and in developing a flavonoid food composition database. SETTING Data on chemi...

Entire phenolic and flavonoid content are the basis for evolution of the preventive role of plant material as compensating factor to oxidative damage caused by free radicals which is a critical etiological aspect responsible for several chronic human ailments, the maximum content of phenol was found in Capsicum annum and the richest source of flavonoid in Lactuca sativa. However the highest fla...

Flavonoids are a large family of compounds associated with a broad range of biologically useful properties. In recent years, synthetic compounds that contain two flavonoid units linked together have attracted attention in drug discovery and development projects. Numerous flavonoid dimer systems, incorporating a range of monomers attached via different linkers, have been reported to exhibit inte...

This paper provides an applicable approach to identifying flavonoid compounds from bamboo leaves extracts, based on the use of the powerful Liquid Chromatography Electrospray Ionization source in combination with hybrid Ion Trap and high-resolution Time-of-flight Mass Spectrometry (LC-(ESI)-IT-TOF/MS). The strategy involves four procedural steps including searching flavonoid components based on...