The author has computed the class groups of all complex quadratic number fields Q(\f^~D) °f discriminant D for 0 < D < 4000000. In so doing, it was found that the first occurrences of rank three in the 3-Sylow subgroup are D = 3321607 = prime, class group C(3) x C(3) x C(9.7) (C(n) a cyclic group of order n), and D = 3640387 = 421.8647, class group C(3) X C(3) X C(9.2). The author has also foun...

The drug target profile proposed by the Medicines for Malaria Venture for a malaria elimination/eradication policy focuses on molecules active on both asexual and sexual stages of Plasmodium, thus with both curative and transmission-blocking activities. The aim of the present work was to investigate whether the class of monovalent ionophores, which includes drugs used in veterinary medicine and...

OBJECTIVES Assessing exposure to physical risk factors during variable noncyclic work can be problematic. The purpose of this study was to modify an existing data reduction method for directly quantifying physical exposures during variable noncyclic work. METHODS Myoelectric activity of the finger flexors of two groups of workers, heavy equipment operators (N=25) and mechanics (N=25), was sam...

In addition to photosynthetic phosphorylation recent work has also provided direct experimental evidence (10-14) for the often asserted but never previously demonstrated capacity of isolated chloroplasts to assimilate CO2 photosynthetically to the level of carbohydrates. CO2 assimilation by isolated chloroplasts was found to be a dark process (15) dependent on a photochemically generated “assim...

The P/2eratio of noncyclic photophosphorylation was investigated in the light of recent reports that it is greater than one and may reflect the existence of two types of electron transport, a phosphorylating and a nonphosphorylating type, superimposed on each other. Our results, obtained under experimental conditions that included those reported to be conducive to high ratios, are consistent wi...

Two imine-based shape-persistent macrocycles containing triphenylene building blocks, along with their noncyclic model compounds, have been synthesized. Their stable conformations are predicted by quantum mechanical calculations and confirmed by 2D NOESY NMR measurements. Compared to the noncyclic model compounds, the macrocycles (3 and 6) show a higher propensity for solution self-assembly due...

Two ionophores (monensin and gramicidin) that carry Na+ into 3T3 cells markedly enhance the rate of 86Rb+ uptake. Ouabain prevents both ionophores from increasing 86Rb+ uptake, indicating that the ionophores activate the Na+,K+ pump. Measurements of 86Rb+ uptake and cell Na+ and K+ over a range of monensin concentrations show that the activity of the Na+,K+ pump in 3T3 cells is limited by the s...