INTRODUCTION Studies of non-specific immunity in infection or immunization with Chlamydophila (Chl.) Psittaci in static experimental models showed changes in parameters of this immunity. The aim of this study was to evaluate selected parameters of non-specific immunity in rabbits immunized with Chl. Psittac. MATERIAL/METHODS The study was performed on rabbits, divided into two groups of 10 an...

Experiments were carried out to determine the effect of partial host immunity against the rodent malaria parasite Plasmodium chabaudi on the transmission success of the parasite. There was a fourfold reduction in both the blood-stage, asexually replicating parasite density and the gametocyte (transmissable stage) density in immunized hosts. Some of the reduction in asexual parasite densities wa...

Spontaneous active immunity to the phenomenon of local skin reactivity to bacterial filtrates has been demonstrated. In one experiment, the immunity was non-specific, while in others it appeared limited to one or two bacterial species. Intradermal vaccination of rabbits with bacterial filtrates induced active immunity to the phenomenon. The specificity of this immunity was tested with graded am...

A study of the recoveries of radioactivity, and of viable bacteria following injection of P(32)-labelled E. coli into the mouse peritoneum, has indicated that the rapid decrease in viable bacteria which occurs is largely due to peritoneal events, and not to the transport of bacteria elsewhere. The serum from mice given lipopolysaccharides 48 hours previously, when used to pretreat bacteria befo...

Within the tumor microenvironment, non-specific innate immune responses can suppress adaptive cytotoxic immunity and hence promote tumor progression. Surgery and trauma provokes high-grade, non-specific inflammatory responses that suppress cell-mediated immunity. Here, the surgical resection of neoplastic lesions is considered in the context of antitumor immunity, providing the rationale for de...

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