In the title hydroxamic acid derivate, C22H16Cl2N2O5, the nitro-substituted benzene ring forms dihedral angles of 14.11 (15) and 16.08 (15)°, with the 4-chloro-benzoyl and 4-chloro-phenyl benzene rings, respectively. The dihedral angle between the chloro-substituted benzene rings is 2.28 (13)°. In the crystal, mol-ecules are linked by weak C-H⋯O hydrogen bonds, forming chains along [100].

We report a case of Goldenhar syndrome and hereditary tyrosinemia type 1 (HTT1), to our knowledge an association not previously described. This case further increases the diversity of observations and clinical descriptions of patients with this complex syndrome. We discuss pathogenetic aspects, and demonstrate further evidence of the effectiveness of 2-(2-nitro-4-trifluoromethyl benzoyl)-1,3-cy...

In the title mol-ecule, C(22)H(17)ClN(2)O(5), the nitro-substituted benzene ring makes a dihedral angle of 79.22 (1)° with the benzoyl ring and 53.03 (1)° with the chloro-substituted benzene ring. An intra-molecular C-H⋯O hydrogen bond occurs. The crystal structure features weak C-H⋯Cl and C-H⋯O inter-actions.

The title compound, C(14)H(12)N(4)O(4), was prepared by the reaction of 2-nitro-phenyl isocyanate with benzoyl-hydrazine. The dihedral angle between the rings is 71.49 (6)) Å. The mol-ecular conformation is stabilized by an intra-molecular N-H⋯O hydrogen bond, generating an S(6) ring. The crystal packing shows N-H⋯O hydrogen bonds.

In the title salt, C(16)H(36)N(+)·C(14)H(8)N(3)O(3)S(-), the torsion angles within the cation reveal that one butyl group displays an anti conformation and the other three butyl groups show gauche conformations. The anion is almost planar, with a largest deviation of 0.166 (6) Å from the least-squares plane (r.m.s. deviation of fitted atoms = 0.052 Å). In the crystal structure, the component io...

Experimental studies on the cleavage of various RNA molecules--poly(U), 3',5''-UpU, 2',5''-UpU, and 3',5''-ApA--catalyzed by imidazole buffers show that there is a sequential bifunctional mechanism. One catalyst species converts the substrate to an intermediate phosphorane, and the second catalyst converts the phosphorane to cleavage products. Detailed steady-state kinetics are presented to det...

Esterification of cellulose with subs t i tu ted or unsubs t i tu ted benzoic acids in t he system of pyridine containing methanesulfonyl chloride at various reaction conditions was investigated. Cellulose could be readily acylated with 2-nitro-, 3-nitro-, 4-nitro-, and 4-azidobenzoic acids to form: 0-(2nitrobenzoyl)cellulose (DS = 3), 0-(3-nitrobenzoyl)celhilose (DS = 3), 0-(4-nitrobenzoyl)cel...

The title compound, C15H11NO4, crystallizes in two polymorphic forms, centrosymmetric monoclinic and chiral ortho-rhom-bic. The geometry of the mol-ecules in the two polymorphs is slightly different, possibly due to inter-molecular inter-actions. There are no classical hydrogen bonding in these two structures. However, a number of C-H⋯O inter-molecular inter-actions, involving both O atoms of t...

The title salt, C(9)H(18)NO(+)·C(7)H(3)ClNO(4) (-), was obtained as an unexpected product of the reaction of 4-chloro-3-nitro-benzoyl isothio-cyanate with pyrrolidine. The six-membered ring of the 4-oxopiperidinium cation adopts a chair conformation. In the crystal structure, two cations and three anions are linked together by inter-molecular N-H⋯O and C-H⋯O hydrogen bonds and arranged diagonal...