nitrite is responsible for some characteristics of cured meat products such as color, flavor and suppressing the outgrowth and production of toxin from clostridium botulinum. despite all of its desired properties, nitrite is responsible for the formation of carcinogenic n-nitrosamine. in this study, nitrite-free and low-nitrite meat curing systems were developed to eliminate or reduce nitrite f...

background and objectives: sodium nitrite and potassium nitrite have been traditionally used for inhibition of clostridium botulinum and also as an agent to stabilize the color of meat products; however, usage of these additives at high levels could lead to toxicity and cancer originating from the formation of nitrosamines. nowadays, application of natural preservatives in order to reduce the n...

background: the assessment of altered nitric oxide (no) availability is of potentially important diagnostic and prognostic significance. the present study is aimed to investigate the effect of l-arginine (as a natural no donor) supplementation on no metabolite in a rabbit model of hypercholesterolemia to find a reliable marker for endothelial no production. methods: white male rabbits (n = 30) ...

background: acute appendicitis is the most common surgical emergency of the childhood. its diagnosis is really challenging. a constellation of through history taking, physical examination, radiographic investigations, and laboratory analysis should be used to balance the risk of delayed operative intervention against the removal of a normal appendix. here a case with misdiagnosis of acute appen...

bachground: paraquat (pq) intoxication manifests with pulmonary edema and fibrosis, heart failure, hepatic failure, and sometimes convulsions. in severe cases, the patients may die within the early hours. at best conditions, the conventional therapeutic methods can only save less than 50% of the victims of intentional pq intoxication. the aim of this study was to evaluate the outcome of new the...

stereologic methods are used to abtain quantitative information about 3-dimensional structures from histologic sections. the aim of the present study was using new and unbiased stereologic techniques to investigate changes in volume and number of glomeruli after chronic lead acetate intoxication both quantitatively and in 3-dimensional spaces.lead is one of the heavy metals that has adverse eff...