BACKGROUND Hydrolyzed polyacrylonitrile (HPAN) has attracted much attention as a hydrogel for a broad range of biomedical applications. Therefore, in this study, we prepared HPAN derivatives with controllable compositions by the radical polymerization of acrylonitrile (AN), methacrylic acid (MAA) and N-isopropylacrylamide (NIPAM) monomers. RESULTS The prepared poly(AN-co-MAA-co-NIPAM) copolym...

Introduction: Polymer gel dosimeters contain chemical materials sensitive to the radiation which are polymerized by the radiation as a function of absorbed dose. So information of spatial dose distribution can be extracted by imaging from irradiated gel. Among imaging techniques, computed tomography (CT) poses as an attractive method because of practical advantages such as acce...

A polymeric photosensitizer, poly(NIPAM-co-RB), consisting of N-isopropylacrylamide and rose bengal units, demonstrates a temperature-controlled changeable oxygenation selectivity by singlet oxygen in water.

In the present work, a new polymeric adsorbent; Poly(NIPAM-co-AN)/clay composite was prepared via in-situ polymerization. The copolymerization of N-isopropylacrylamide, acrylonitrile and calculated clay (about 5% w/w) were carried out at 65°C in presence 10 mL 1,4-dioxane using AIBN as an initiator. Characterization P(NIPAM-co-AN)/clay determined by FT-IR techniques. NIPAM-AN/clay has been used...

background: in this study the basic radiation properties of n-isopropylacrylamaide polymer gel dosimeter were determined together with verification of its soft tissue equivalency. materials and methods: the nipam gel was prepared and irradiated approximately 2 h after manufacturing. the magnetic resonance (mr) images were made 24 h after irradiation. the nuclear magnetic resonance (nmr) respons...

The aim of this study was to characterize a pH-sensitive liposome formulation bearing a terminally alkylated N-isopropylacrylamide (NIPAM) copolymer with regard to its pH responsiveness, surface properties, and pharmacokinetics. The interacting forces between two lipid bilayers bearing the anchored NIPAM copolymer were measured with a surface force apparatus. The pH-triggered content release wa...

We report the design and synthesis of a tetraphenylethene substituted with naphthalimide at the 4, 6 positions, named NI-2TPE. NI-2TPE exhibits strong solvent-dependent emission properties with combined ICT and AIE characteristics in THF-H2O systems. This probe was used directly on test papers to distinguish normal organic solvents using their emission colours under UV light based on its AIE an...

Fluorescent carbon nanoparticles (FCNPs) have been successfully immobilized into poly(N-isopropylacrylamide-co-acrylamide) [poly(NIPAM-AAm)] nanogels based on one-pot precipitation copolymerization of NIPAM monomers with hydrogen bonded FCNP-AAm complex monomers in water. The resultant poly(NIPAM-AAm)-FCNP hybrid nanogels can combine functions from each building block for fluorescent temperatur...

INTRODUCTION At present, the polymer gel dosimeter is considered to be the best possible dosimeter for measuring 3-dimesional radiation dose distribution in radiotherapy. These gels are normally toxic; therefore, manufacturing, handling and discarding them require special attention. In order to find less toxic recipe, N-isopropyle acrylamide polymer gel (NIPAM) was introduced. In this study, th...

In this study, a two-level full factorial design was used to identify the effects of the interactions between compositions in an N-isopropylacrylamide (NIPAM) gel dosimeter involving the following variables: (A) gelatin, (B) NIPAM, (C) the crosslinker N, N'-methylene-bis-acrylamide (Bis), and (D) the antioxidant tetrakis (hydroxymethyl) phosphonium chloride (THPC). The dose range was from 0 Gy ...