نتایج جستجو برای: neutrophil gelatinase associated lipocalin
تعداد نتایج: 1554424 فیلتر نتایج به سال:
OBJECTIVE To test whether perioperative sodium bicarbonate infusion can attenuate postoperative increases in serum creatinine in cardiac surgical patients. DESIGN Double-blind, randomized controlled trial. SETTING Operating rooms and intensive care unit at a tertiary hospital. PATIENTS Cohort of 100 cardiac surgical patients at increased risk of postoperative acute renal dysfunction. IN...
Introduction Diabetic nephropathy is associated with specific histological changes. Early detection of poor glomerular and tubular function can be achieved with biomarkers of diabetes. The aim of this study was to evaluate the accuracy of kidney dysfunction biomarkers in type 2 diabetes (T2D). Methods Patients with T2D were grouped according to their glycated hemoglobin level. Patients' urine...
Chronic kidney disease (CKD) is characterized by a loss of renal function associated with inflammatory and fibrotic processes, which can progress high levels proteinuria. The increase proteinuria recognized risk factor in patients, experimental studies suggest that it to the pro-inflammatory phenotype drives fibrosis during CKD progression. rise neutrophil gelatinase-associated lipocalin (NGAL)...
A 25-kDa protein was found to be associated with purified human neutrophil gelatinase. Polyclonal antibodies raised against gelatinase not only recognized gelatinase but also this 25-kDa protein. Specific antibodies against the 25-kDa protein were obtained by affinity purification of the gelatinase antibodies. Immunoblotting and immunoprecipitation studies demonstrated the 135-kDa form of gelat...
OBJECTIVES Video laparoscopic bariatric surgery is the preferred surgical technique for treating morbid obesity. However, pneumoperitoneum can pose risks to the kidneys by causing a decrease in renal blood flow. Furthermore, as in other surgical procedures, laparoscopic bariatric surgery triggers an acute inflammatory response. Neutrophil gelatinase-associated lipocalin is an early and accurate...
Acute kidney injury is a common and significant problem that occurs in a wide variety of clinical settings. Cardiac surgery-associated acute kidney injury continues to be a well-recognized complication of cardiac surgery with associated morbidity and mortality. A lack of early biomarkers for acute kidney injury has prevented timely interventions to mitigate the effects of acute kidney injury. B...
BACKGROUND AND OBJECTIVES A temporary deterioration in renal function during pneumoperitoneum has been reported, but the extent is not known. A new marker for the early detection of renal injury, neutrophil gelatinase-associated lipocalin (NGAL), has been shown to increase in various conditions that affect renal function. This study was conducted to explore detrimental effects of pneumoperitone...
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