نتایج جستجو برای: neuroprotectant

تعداد نتایج: 379  

Journal: :Stroke 2004
Helmi L Lutsep

Strokes still cause death every 3.3 minutes in the United States and are a leading cause of disability. Although the thrombolytic tissue plasminogen activator has been available for the treatment of ischemic stroke since 1996, no neuroprotectant acute stroke treatment strategy to preserve dysfunctional neurons in the ischemic penumbra has shown efficacy in clinical trials. New approaches for th...

Journal: :The Journal of Thoracic and Cardiovascular Surgery 2006

Journal: :Stem cell research 2017
Claudia Wing Masaaki Komatsu Shannon M Delaney Matthew Krause Heather E Wheeler M Eileen Dolan

The generation of induced pluripotent stem cells (iPSCs) and differentiation to cells composing major organs has opened up the possibility for a new model system to study adverse toxicities associated with chemotherapy. Therefore, we used human iPSC-derived neurons to study peripheral neuropathy, one of the most common adverse effects of chemotherapy and cause for dose reduction. To determine t...

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