BACKGROUND Patients with Parkinson disease (PD) may present with various types of pain. In some instances, no cause can be identified and pain is considered a primary disorder (primary central pain [PCP]). We hypothesized that PCP in patients with PD (PD-PCP) may be due to a dysfunction of pain pathways or the processing of pain inputs in the CNS. METHODS We carried out a psychophysical and n...

BACKGROUND Deep hypothermia is an important cerebral protectant and is critical in procedures requiring circulatory arrest. The purpose of this study was to determine the factors that influence the neurophysiologic changes during cooling before circulatory arrest, in particular the occurrence of electrocerebral silence. METHODS In 109 patients undergoing hypothermic circulatory arrest with ne...

Investigation of brain disorders especially epilepsy and impaired cognitive functions are the most common clinical application of neurophysiologic signals. EEG signals reflect the activity of brain and are capable of assessing the brain condition during abnormalities. In this study we have investigated the potential of two different algorithms (back propagation and radial basis function) of neu...

R indicates that long­term alcohol abuse1 can impair virtu­ ally all of the brain’s information­ processing (cogni­ tive) functions. Much of this research has been limited to the study of alcoholic men, perhaps, in part, because for many years, the primary locations for such research were Veterans’ Administration hospitals. This situation has changed in recent years. With increasing treatment a...

There is ample electrophysiological evidence of attention dysfunction in the EEG/ERP signal of major depressive disorder (MDD), bipolar disorder, and schizophrenia. The reduced attention-related ERP waves show much similarity between MDD, bipolar disorder, and schizophrenia, raising the question whether there are similarities in the neurophysiologic process that underlies attention dysfunction ...

Alien Hand Syndrome is defined as unwilled, uncontrollable, but seemingly purposeful movements of an upper limb. Two major criteria for the diagnosis are complaint of a foreign limb and complex, autonomous, involuntary motor activity that is not part of an identifiable movement disorder. After a cerebrovascular accident in the corpus callosum, the parietal, or frontal regions, various abnormal ...