Microdialysis is a technique for sampling the chemistry of the interstitial fluid of tissues and organs in animal and man. It is minimally invasive and simple to perform in a clinical setting. Although microdialysis samples essentially all small molecular substances present in the interstitial fluid the use of microdialysis in neurointensive care has focused on markers of ischemia and cell dama...

© 2015 Indian Journal of Critical Care Medicine | Published by Wolters Kluwer Medknow Raised intracranial pressure (ICP) is a complication not just of traumatic brain injury and other acute cerebral insults, but also of a number of general medical conditions. Monitoring of ICP is of paramount importance in Neurointensive Care Unit. Increased ICP causes brain insult which may be associated with ...

The cerebral microcirculation consists of a complex network of small blood vessels that support nerve cells with oxygen and nutrition. The blood flow and oxygen delivery in the microcirculatory blood vessels are regulated through mechanisms which may be influenced or impaired by disease or brain damage resulting from conditions such as brain tumors, traumatic brain injury or subarachnoid hemorr...