Recurrent, site-specific chromosome translocations and other cytogenetic abnormalities are being described in ever-increasing numbers and types of human tumors. Primary brain tumors are the most common pediatric solid tumor and differ from those of adults in both histology and clinical behavior. We examined chromosomes from 21 primary pediatric brain neoplasms grown in short-term tissue culture...

We report the case of a 44-year-old man who experienced a fatal and untreatable delayed vasospasm after resection of a recurrent temporal IV grade primitive neuroectodermal tumor (PNET). The histological analysis demonstrated a rare rhabdoid variant of the tumor with a diffuse myxoid degeneration; molecular investigations demonstrated an upregulation of IL-1β and IL-6 expression in the recurren...

Neuroblastoma-like schwannoma is known as a rare unusual variant of with difficulties differential diagnosis neuroblastoma, Ewing sarcoma/peripheral neuroectodermal tumor and other cutaneous small round cell tumors. Herein, we describe neuroblastoma-like that was presented painless lesion on the dorsal side left hand in 39-year-old woman. Composed collagen fibers central core rosettes diffuse e...

Primitive neuroectodermal tumor (PENETs) is an uncommon malignancy of bone and soft tissue witch rarely occurs in the kidney. In more than 90% of the cases, the tumor cells relieves a balanced translocation (11; 22) (q24; q12). Immunohistochemical staining may be required for diagnosis of PENET. The cells of tumor express CD99, vimentin, NSE, FL1 but do not express Ck, LCA, myogenin, and WT1. W...

PURPOSE To present the clinical, radiological, histopathological, immunohistochemical features and the follow-up of orbital primitive neuroectodermal tumors (PNETs) in pediatric patients along with a review of the literature. METHODS A retrospective analysis of all diagnosed cases of orbital PNET was done. Patients' ophthalmic findings, imaging, immunohistochemistry, metastatic work-up, treat...

Primary primitive neuroectodermal tumors (PNET) are rare malignant tumors, affecting mostly children and adolescents. Only three cases of primary breast PNETs have been reported in the medical literature, with none in Korea. We present a case of a primary PNET of the breast in a 33-year-old woman, with imaging and immunohistopathology findings.

Melanotic neuroectodermal tumour of infancy is a rare neoplasm of neural crest origin, predominantly affecting the anterior maxilla of infants. Treatment generally consists of surgical excision. Long-term follow-up is important since recurrence and malignant transformation have been reported. The literature about melanotic neuroectodermal tumour of infancy is reviewed and a case occurring in a ...

Melanotic neuroectodermal tumor of infancy (MNETI) is also known as pigmented neuroectodermal tumor of infancy, melanotic prognoma, retinal anlage tumor, pigmented epulis of infancy and congenital melanocarcinoma. It is a rare neoplasm, occuring primarily in maxilla and mandible of infants. Till 1990 about 200 cases had been recorded in world literature(l,2). We report a case with this entity.