Neuroblastoma is a nervous system malignancy. The extension of intra-abdominal neuroblastoma to the spinal canal is a rare condition. In this case report, we present a patient with monoplegia and a huge intra-abdominal mass with intra spinal extension and cord compression.

Abstract Background Neuroblastoma is a childhood neural crest tumor showing large clinical and genetic heterogeneity, one form displaying 11q-deletion very aggressive. It has been shown that results in decreased expression of DLG2 , gene residing the deleted region. number different isoforms with main difference presence or absence L27 domain. The domain containing DLG proteins can complexes CA...

Abstract Deubiquitinating enzymes are increasingly recognized to play important roles in cancer, with many acting as oncogenes or tumor suppressors. In this study, we employed a bioinformatics approach screen for from family involved cancer and found USP24 potent predictor of poor outcomes neuroblastoma, an aggressive childhood cancer. resides region commonly deleted yet was independently assoc...

the spontaneous regression of neuroblastoma to ganlioneuroma is a rare occurrence. reviewing the literature, we found no more than 12casesreported.'•2.9.,o.'4.1s we report a case of metastatic neuroblastoma of multifocal skeletal and soft tissue areas with gross deformities which regressed to ganglioneuroma, with good prognosis.

Abstract Neuroblastoma (NB) is an embryonal deadly cancer in childhood driven by MYC or MYCN‐driven oncogenic signaling. The amplification of MYCN leads to malignant progression NB and poor prognosis. Traditional chemotherapy still a standard treatment for NB. Most the cytostatic drugs take function anti‐neuroblastoma. However, children with exhibit different clinical outcome variability biolog...

O neuroblastoma metastático para o sistema nervoso central é raro. São relatados dois casos de supra-renal em duas crianças brancas, do sexo feminino, com 13 meses e 24 idade, respectivamente. A primeira apresentou metástases intracranianas durante tratamento disseminado. segunda paciente sintomatologia inicial hipertensão intracraniana tumor abdominal primário foi descoberto quando a criança a...

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neuroblastoma is the most common extracranial solid tumor in childhood. in different classification of neuroblastomas, a subset of undifferentiated or poorly differentiated tumors with bizarre histological features has been mentioned. a 3-year-old girl presented with abdominal pain. her haematological and biochemical parameters were normal except her urinary vanelylmandelic acid level was elevat...

PURPOSE Neuroblastoma is a childhood cancer that exhibits either a favorable or an unfavorable phenotype. Favorable neuroblastoma genes (EPHB6, EFNB2, EFNB3, NTRK1, and CD44) are genes whose high-level expression predicts favorable neuroblastoma disease outcome. Accordingly, the forced expression of these genes or their reactivation by gene silencing inhibitors in unfavorable neuroblastoma cell...

Neuroblastoma is a disease that observed in early childhood, originating from the sympathetic nervous system and very difficult to treat. Etoposide, topoisomerase 2 inhibitor, one of agents used cancer treatment. Galangin puerarin are plant-based antioxidants with anticancer properties. Since apoptosis induction methods treatment, evaluation mRNA expression levels apoptosis-related genes aimed ...