نتایج جستجو برای: neuraminidase

تعداد نتایج: 5883  

Journal: :The Journal of clinical investigation 1990
S A Dolan L H Miller T E Wellems

The human malaria parasite Plasmodium falciparum demonstrates variability in its dependence upon erythrocyte sialic acid residues for invasion. Some lines of P. falciparum invade neuraminidase-treated or glycophorin-deficient red blood cells poorly, or not at all, while other lines invade such cells at substantial rates. To explore the molecular basis of non-sialic acid dependent invasion, we s...

Journal: :Influenza and Other Respiratory Viruses 2011

Journal: :Journal of virology 2005
José Agustín López Antonio José Maldonado Marlene Gerder José Abanero Juan Murgich Flor H Pujol Ferdinando Liprandi Juan Ernesto Ludert

Infection by some rotavirus strains requires the presence of sialic acid on the cell surface, its infectivity being reduced in cells treated with neuraminidase. A neuraminidase treatment-resistant mutant was isolated from the porcine rotavirus strain OSU. In reassortant strains, the neuraminidase-resistant phenotype segregated with the gene coding for VP4. The mutant retained its capacity to bi...

Journal: :Infection and immunity 1983
H Shibuta A Nozawa T Shioda T Kanda

By a sensitive fluorometric assay method, we could definitely demonstrate neuraminidase activity for two variants of parainfluenza 3 virus, M and SC, which were previously shown to have no detectable neuraminidase activity. The enzyme activities of these viruses were very similar to each other, showing a much lower catalytic rate, a much higher Km value, and a more acidic pH optimum than those ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1986
O T Mueller W M Henry L L Haley M G Byers R L Eddy T B Shows

The inherited human disorders sialidosis and galactosialidosis are the result of deficiencies of glycoprotein-specific alpha-neuraminidase (acylneuraminyl hydrolase, EC 3.2.1.18; sialidase) activity. Two genes were determined to be necessary for expression of neuraminidase by using human-mouse somatic cell hybrids segregating human chromosomes. A panel of mouse RAG-human hybrid cells demonstrat...

Journal: :GSC biological and pharmaceutical sciences 2023

Several phytochemicals exhibited high level of antiviral activity. Medicinal plant possessed activity via many mechanisms included inhibition viral replication, the assembly intracellular infectious virus particles, infectivity, RNA polymerase, DNA neuraminidase, protease, reverse transcriptase and protein expression other mechanisms. The current review discuss medicinal plants with their action.

2015
Zekun Liu Junpeng Zhao Weichen Li Xinkun Wang Jingxuan Xu Jin Xie Ke Tao Li Shen Ran Zhang

As a new strain of virus emerged in 2013, avian influenza A (H7N9) virus is a threat to the public health, due to its high lethality and pathogenicity. Furthermore, H7N9 has already generated various mutations such as neuraminidase R294K mutation which could make the anti-influenza oseltamivir less effective or ineffective. In this regard, it is urgent to develop new effective anti-H7N9 drug. I...

Journal: :iranian journal of microbiology 0
hassan norouzian department of clinical sciences, faculty of veterinary medicine, lorestan university, khorram-abad,iran. mohsen bashashati department of clinical sciences, faculty of veterinary medicine, university of tehran, tehran, iran. mehdi vasfimarandi department of clinical sciences, faculty of veterinary medicine, university of tehran, tehran, iran.

backgrounds and objectives: classified as low pathogenic avian influenza (lpai) viruses, the h9n2 subtype causes severe respiratory disease in poultry farms and occasional respiratory disease in humans. in this study, the neuraminidase (na) gene of three avian influenza (ai) h9n2 strains isolated from poultry farms in iran during 2010-11, as well as other reported iranian h9n2 isolates, were ge...

Journal: :Journal of medical genetics 1987
I D Young E P Young J Mossman A R Fielder J R Moore

A 12 year old boy with neuraminidase deficiency (sialidosis, mucolipidosis I) is described. His clinical features included coarse facies, cherry red spot, ataxia, myoclonus, and dysotosis multiplex. The level of neuraminidase activity in cultured fibroblasts was very low and intermediate levels were observed in both parents. The clinical disorders associated with neuraminidase deficiency are re...

Journal: :Journal of microbiological methods 2013
Paulo R G R de Assis Viviane Nakano Gerusa N A Senhorinho Mario J Avila-Campos

Neuraminidase was produced by 32.1% and 28.5% of Porphyromonas from dogs with and without periodontitis, respectively; and by 31.8% of bacteria from humans. The presence of neuraminidase in Porphyromonas spp. suggests that this enzyme can be involved with the pathogenesis of the periodontal disease, and the use of this assay to detect the neuraminidase production in oral Porphyromonas species i...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید