objective: to assess the neuroprotective effects of local administration of 17- beta- estradiol on nerve regeneration. methods: sixty female wistar rats were overiectomized and divided into four experimental groups (n = 15), randomly: in autograft group a segment of sciatic nerve was transected and re-implanted reversely. in sham-surgery group sciatic nerve was exposed and manipulated. in trans...

  Abstract   Background : Although, different studies on end-to-side nerve repair, results are controversial. The importance of this method in case is unavailability of proximal nerve. In this method, donor nerves also remain intact and without injury. In compare to other classic procedures, end-to-side repair is not much time consuming and needs less dissection. Overall, the previous studies i...

background: olfactory ensheathing glia (oeg) has been shown to have a neuroprotective effect after being transplanted in rats with spinal cord injury. this study was conducted to determine the possible beneficial results of olfactory mucosa transplantation (omt) which is a source of oeg on functional recovery and axonal regeneration after transection of the sciatic nerve. methods: in this study...

how to cite this article: toopchizadeh v, barzegar m, habibzadeh a. sciatic nerve injection palsy in children, electrophysiologic pattern and outcome: a case series study. iran j child neurol. summer 2015;9(3):69-72. abstract sciatic nerve injury is one of the frequent mononeuropathies in children that occurs due to different causes such as nerve compression, trauma and stretch during surgery. ...

Background: Olfactory ensheathing glia (OEG) has been shown to have a neuroprotective effect after being transplanted in rats with spinal cord injury. This study was conducted to determine the possible beneficial results of olfactory mucosa transplantation (OMT) which is a source of OEG on functional recovery and axonal regeneration after transection of the sciatic nerve. Methods: In this study...

Objective(s): To investigate the effect of topical administration of alpha-lipoic acid into chitosan conduit on peripheral nerve regeneration using a rat sciatic nerve transection model. Materials and Methods: Forty five Wistar rats were divided into three experimental groups randomly. A 10-mm gap of sciatic nerve was bridged with a chitosan conduit following surgical preparation and anesthesia...

a common cause of peripheral nerve injury is trauma. the positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. in this experiment, the effect of intraperitoneal administration of ubiquinone (coq10) on an acute experimentally sciatic nerve crush was studied in a rat model. forty-five male wistar rats, weighing between 160-180 g were u...

Sciatic functional index (SFI) as a behavioral method was used to assess the functional recovery following experimentally-induced various injuries in the sciatic nerve, spinal cord, and brain. In the present study, the functional recovery after induction of injury in the sciatic nerve was investigated in rats using SFI. Twenty-four rats were divided into three groups including sham-operated (SS...

OBJECTIVES To systematically record rat facial nerve recovery following crush injury to the main trunk with respect to ocular and vibrissial function and to compare the rates of facial and sciatic nerve recovery from crush injury in the same animals. This serves as a means of validating the functional parameters of facial nerve recovery against the well-known measure of hind limb function, the ...

BACKGROUND/AIM Nerve transfers in cases of directly irreparable, or high level extensive brachial plexus traction injuries are performed using a variety of donor nerves with various success but an ideal method has not been established. The purpose of this study was to analyze the results of nerve transfers in patients with traction injuries to the brachial plexus using the thoracodorsal and med...