objectives: the idiopathic minimal change nephritic syndrome (nephrosis) is responsible in 80% of nephritic syndromes in children. it is a clinical entity characterized by inter and outer renal parameters. main factor in glomerolar damages is proteinuria and the role of ige is possible. aim: in this research, serum ige concentrations were measured in children with nephrosis in three stages: rel...

BACKGROUND ACE inhibition exerts an antiproteinuric and renoprotective effect. However, residual proteinuria is often present. As residual proteinuria is associated with a poor renal outcome, identification of its determinants is important. We found previously that the systemic sequelae of proteinuria enhance renal damage in untreated nephrotic rats. The impact of systemic nephrosis on renal th...

attenuated the decreases in mRNA levels for HSPG (P<0.01) in glomeruli of PAN-injected rats. Enalapril Background. We previously reported that mRNA levels for extracellular matrix (ECM) components had little e ect on increased glomerular mRNA levels for MMP-2 and TIMP-1 in PAN nephrosis, whereas and endothelin (ET)-1 are upregulated in glomeruli of puromycin aminonucleoside (PAN) nephrosis. FR1...

acute renal failure is one of the side effects while using intravenous immunoglobulins. this complication is also observed with iodinated contrast media. herein, we describe a patient with acute renal failure who received intravenous immunoglobulins and iodinated contrast media concomitantly. both drugs are responsible for osmotic nephrosis. the same effect on renal cells may explain a synergis...

OBJECTIVES To investigate the question of whether there is an association between exposure to silica or respirable glass fibre and mortality from nephritis or nephrosis among workers in fibrous glass wool manufacturing facilities. METHODS A case-control study with cases and controls derived from the Owens Corning mortality surveillance system. Two case-control analyses were carried out, one w...

Uttley, W. S., Maxwell, H., and Cash, J. D. (1974). Archives of Disease in Childhood, 49, 137. Fibrin/fibrinogen degradation products in children with renal disease. Fibrin/fibrinogen degradation products (FDP) were measured in the serum and urine of children with various forms of renal disease. Serum FDP was raised both with nephrosis and with active proliferative nephritis. Urine FDP was rare...

The association between nephrotic syndrome (NS) and a hypercoagulable state has been demonstrated. Controlling the blood clotting activity may therefore be attractive for patients with nephrosis in terms of thromboembolism prophylaxis. We herein report a 75-year-old woman with minimal change disease who developed pains in the right back, groin, and thigh because of retroperitoneal bleeding duri...