There is no consistent evidence of resistance of Atlantic salmon (Salmo salar) to amoebic gill disease (AGD), despite either a prior history of AGD, passive immunisation or active immunisation. Here, fish were bathed in amoebae antigens from either an avirulent in vitro cultured strain or wild-type Neoparamoeba pemaquidensis and challenged with gill-derived amoebae 27 days post-treatment. Neith...

Neoparamoeba perurans is a free-living protist that can cause Amoebic Gill Disease (AGD) in number of teleost fish species and responsible for substantial losses farmed Atlantic salmon various locations world-wide. The intimate relationship the amoeba with bacteria present challenges its laboratory culture drug discovery programmes. Herein, we report our findings on live close association N. pe...

Amoebic gill disease (AGD) is a significant issue in Atlantic salmon mariculture. Research on the development of treatments or vaccines uses experimental challenges where exposed to amoebae concentrations ranging from 500 5,000/L. However, water N. perurans affected farms are much lower. The lowest concentration previously reported cause AGD was 10/L. Here, we report that as low 0.1/L can AGD. ...