In a previous study, we showed that exposure of rats to dexamethasone (Dex) selectively in late pregnancy produces permanent induction of hepatic phosphoenolpyruvate carboxykinase (PEPCK) expression and hyperglycaemia in the adult offspring. The mechanisms by which glucocorticoids cause this programming are unclear but may involve direct actions on the fetus/neonate, or glucocorticoids may act ...

OBJECTIVE The authors reviewed the risks and benefits regarding the use of psychiatric medications during breast-feeding as they relate to the health and well-being of mothers and their infants. Strategies are discussed to limit infant exposure to a medication while effectively treating the nursing mother. METHOD A MEDLINE search of the literature since 1955 was conducted to determine the use...

Nursing care of the neonate in the neonatal intensive care unit (NICU) is complex, due in large part to various physiological challenges. A newer and less well-known physiological consideration is the neonatal microbiome, the community of microorganisms, both helpful and harmful, that inhabit the human body. The neonatal microbiome is influenced by the maternal microbiome, mode of infant birth,...

The miracle of antibiotics is hard to exaggerate. Each day, in every corner of the world, antibiotics improve, or could be improving outcomes in the septic neonate, the child with pneumonia, the new mother after a complicated delivery, the patient undergoing surgery, the nursing home resident with a urinary tract infection, the patient being treated of cancer, or the trauma patient on life supp...

Yu, V. Y. H. (1975). Archives of Disease in Childhood, 50, 500. Effect of body position on gastric emptying in the neonate. The effect of body position on gastric emptying was investigated in 48 neonates. The rate of gastric emptying is the same for healthy term, preterm, and small-for-dates infants. Infants with respiratory distress syndrome have delayed gastric emptying and a high incidence o...

Abstract Background: Allergic asthma is associated with lung microbial dysbiosis. We hypothesized that the microbiome from lungs of allergy-predisposed mouse pups sufficient to predispose development allergy. inflammation in allergic dams blocked by α-tocopherol supplementation dam during gestation and nursing, but it unknown whether alters composition lung. Methodology: Mouse were predisposed ...

INTRODUCTION Breast feeding has long term effects on the developing immune system which outlive passive immunization of the neonate. We have investigated the transfer of milk immune cells and examined the result of transfer once the recipients were adult. METHODS Non-transgenic mouse pups were foster-nursed by green fluorescent protein (GFP) transgenic dams for 3 weeks and the fate of GFP+ ce...

Genotoxic exposure to chemical substances is common, and nursing mothers could transmit harmful substances or their metabolites to their offspring through breast milk. We explored the possibility of determining genotoxic effects in the erythrocytes of breastfeeding rat pups whose mothers received a genotoxic compound while nursing. Ten groups of female rats and five pups per dam were studied. T...

introduction: at the end of their education, nursing students have to acquire the minimum capabilities, essential for their professional job. the aim of this study was to determine the achievement of minimum learning requirements by midwifery students in school of nursing and midwifery of isfahan university of medical sciences. methods: a descriptive study as an educational evaluation based on ...