INTRODUCTION Central nervous system (CNS) infections are life-threatening diseases caused by viral, bacterial, parasitic and fungal microorganisms. The aim of this study was to determine the accuracy of universal polymerase chain reaction (PCR) for the detection of bacterial meningitis among patients who were referred to Koodakan Hospital in Bandar Abbas because they were suspected of having th...

Background: Enterovirus (EV) infections are one of the most common causes of aseptic meningitis in pediatrics. To diagnose EV meningitis, virus isolation in cell cultures is often time consuming and lacks sensitivity to be of clinical relevance. This makes the virus culture results difficult to interpret. The rapid detection of EVs in cerebrospinal fluid (CSF) by molecular diagnostic techniques...

Introduction: Bacterial meningitis is still one of the most dangerous infectious diseases and causes serious complications and mortalities in children. The aim of this study was to identify the most common of bacterial agents causing meningitis in children under 10 years old and to detect their resistance to antibiotics in patients who referred to the educational hospital of Hamadan. Materials...

The Limulus amoebocyte lysate endotoxin assay was evaluated as a method for rapid diagnosis of acute bacterial meningitis in a series of 305 patients. The results of Limulus assays on cerebrospinal fluid (CSF) samples from these patients were compared with the results for each patient of routine bacterial cultures and Gram stains. Positive Limulus tests were obtained on initial CSF specimens fr...

background optimal use of the clinical examination aids physicians in identifying patients at risk for meningitis. the low specificity of the meningeal signs may be due to the presence of cervical arthritis and spondylosis. one of the most sensitive maneuvers in the diagnosis of meningitis is jolt accentuation of headache. patients and methods a descriptive research was performed on suspected a...

viruses are the most common causes of aseptic meningitis. early detection, treatment and management of viral meningitis are priority. this study aimed to evaluate common viral meningitis in children referred to taleghani pediatrics hospital in gorgan, south east of caspian sea, iran. in this descriptive study csf and blood samples were taken from 40 children with negative bacterial culture who ...

BACKGROUND Seizures are one of the most important neurologic complications of human immuno-deficiency virus (HIV)-negative cryptococcal meningitis. A better understanding of the risk associated factors can help predict those who will require treatment. METHODS This 22-year retrospective study enrolled 180 patients. Prognostic variables independently associated with seizures or fatality were a...

Although a frequent and extensively described cause of meningitis in neonates, grain-negative meningitis is unusual in adults. Most of the cases reported are secondary to trauma or surgery. Spontaneous cases are rare and almost always have a primary tocus of infection elsewhere Which needs to be explored. We report the case of a young woman with gram—negative meningitis secondary to rupture of ...

Background and Aim. Bacterial meningitis is a lethal, disabling endemic disease needing prompt antibiotic management. Gram stained smears is rapid accurate method for diagnosis of bacterial meningitis. In cases of negative gram stained smears diagnosis is delayed till culture results. We aim to assess the role of clinical presentations and routine CSF analysis in the cost-effective rapid diagno...