The efficacy of different extracts of neem leaf on seed borne fungi Aspergillus, Rhizopus and chemical characterization of the neem leaf extracts were studied in vitro on the culture medium. The growth of both the fungal species was inhibited significantly (p<0.01) and controlled with both alcoholic and water extract of all ages and of the concentrations used. The alcoholic extracts of neem lea...

BACKGROUND Different strains of influenza virus are affecting a large number of people worldwide. Many synthetic antiviral medicines are available for influenza virus in the market. But still there is a need for the development of universal drugs against these strains of influenza virus. METHODS For this purpose conserved residues within the influenza virus nucleoprotein have been retrieved. ...

Malaria is a major public health problem in the world because it can cause of death in patients. Malaria-associated renal injury is associated with 45% of mortality in adult patients hospitalized with severe form of the disease. Therefore, new plant extracts to protect against renal injury induced by malaria infection are urgently needed. In this study, we investigated the protective effect of ...

The present study was carried out to screen and evaluate antimicrobial activity of leaf and bark extracts of Azadirachta indica. Ethanol and aqueous extract of leaves and barks of A. indica (Neem) were tested against Escherichia coli and Staphylococcus aureus which are known to be resistant to various antibiotics. Neem materials which were used during this study were collected from Bugesera dis...

BACKGROUND E. faecalis is the predominant micro-organism recovered from root canal of the teeth where previous endodontic treatment has failed. Thorough debridement and complete elimination of micro-organisms are objectives of an effective endodontic treatment. For many years, intracanal irrigants have been used as an adjunct to enhance antimicrobial effect of cleaning and shaping in endodontic...

The effects of neem oil (Nimbecidine 0.03% Aza) and water extracts of neem seed and leaf on African bollworm, Helicoverpa armigera were studied each at three concentration levels (2.5%, 5% and 10%) under laboratory condition. Square dip and larval immersion experiments were conducted using Completely Randomized Design in three replications. In square dip experiment, high mortalities were statis...

Diabetes Mellitus is affecting people of all age groups worldwide. Many synthetic medicines available for type 2 diabetes mellitus in the market. However, there is a strong requirement for the development of better anti-diabetes compounds sourced especially from natural sources like medicinal plants. The extracts from the leaves of neem (Azadirachta indica) is traditionally known to have anti-d...

In vitro trials were conducted to evaluate the effect of Azadirachtaindica (neem) extracts on mycelial growth, sporulation, morphology and ochratoxin A production by P. verrucosum and P. brevicompactum. The effect of neem oil extract from seeds and leaf was evaluated at 0.125; 0.25 and 0.5% and 6.25 and 12.5 mg/mL, respectively, in Yeast Extract Sucrose (YES) medium. Ochratoxin A production was...

The present study was designed to investigate the effect of Azadirechta indica (Neem) leaf extract on restraint-induced behavioral deficits and changes in serotonin metabolism in rats. Exposure to a single stress decreased food intake, growth rate and elicited anxiogenic-like behavior on an elevated plus maze. Prior administration of neem leaf extract @ 1 ml/kg for 5 days attenuated stress indu...

Control programs using conventional insecticides to target anthropogenic mosquito habitats are very expensive because these habitats are widespread, particularly in cities of most African countries. Additionally, there are serious environmental concerns regarding large-scale application of most conventional insecticides. Clearly there is a need for alternative methods that are more effective, l...