BACKGROUND A new electronic mesh nebulizer, eMotion is known to have higher performance compared to conventional nebulizers. However, there are some concerns about whether too much delivered dose might cause side effects with higher frequency. METHODS To evaluate the safety and usefulness of the nebulizer, we measured changes in heart rates and lung functions of 73 asthmatic children when the...

Many methods of testing nonspecific bronchial responsiveness have been devised, since Curry first demonstrated the heightened bronchial responsiveness of asthmatics to histamine. The preferred rou1e of administration of bronchoconstrictors at the presem Lime is by inhalation, rather than systemically, in order to minimize unacceptable side effects. The agents inhaled have included irritants, ch...

Introduction Basic Concepts of Aerosol Therapy Inertial Impaction Gravitational Sedimentation Diffusion The Nebulizer The Metered Dose Inhaler Differences during Mechanical Ventilation The Ventilator-Patient Interface Breath Configurations The Airway The Environment The Assessment Evaluation of Lower Respiratory Tract Aerosol Delivery with Bench Models of Mechanical Ventilation Aerosol-Generati...

In the later half of the 20th century, nebulized therapy was in decline, but in the 21st century the prospects for the expanded use of nebulized therapy within respiratory medicine look bright. The advent of mesh nebulizers, which combine the universal applicability of the nebulizer in the treatment of all respiratory patients with the convenience of portable inhaler use, is ideally timed to ca...

BACKGROUND Nebulization is a common method of medical aerosol generation and it is largely used by adults and children all over the world, both for emergency treatment of acute illness and for long-term home treatment of lung diseases. The aim of this study was to determine the differences in nebulization of inhaled corticosteroids among four representative types of compressor/nebulizers. MET...

The aim of our study was to verify if the type of nebulizer used could influence the results of aerosol therapy with beclomethasone dipropionate (BDP) in mild allergic asthma. We assigned 27 asthmatics allergic to grasses to 3 groups and treated them from May to July 1998 with aerosol therapy with BDP (800 microg) b. i. d. via nebulizer + pMDI salbutamol (200 microg) if necessary. Each group us...

Conventional gravimetric (weight loss) calibration of jet nebulizers overestimates their aerosol output by up to 80% due to unaccounted evaporative loss. We examined two methods of measuring true aerosol output from jet nebulizers. A new adaptation of a widely available clinical assay for lithium (determined by flame photometry, LiCl method) was compared to an existing electrochemical method ba...

BACKGROUND Continuous albuterol nebulization has become the standard of care for patients with status asthmaticus. Predictable albuterol delivery is paramount for effective therapy. We compared the aerosol characteristics, solution output, and albuterol output of 4 brands of large-volume nebulizer. METHODS We studied 6 units of the following nebulizer brands: AirLife Misty Finity (Cardinal He...

Pseudomonas cepacia strains were isolated from the water reservoirs of unheated nebulizers in a hospital setting. The isolates were characterized by morphology, biochemical tests, and antibiotic susceptibility patterns. An interesting feature of these organisms was their capacity for sustained multiplication in either doubly deionized or doubly distilled water as well as 5% dextrose or 0.9% sal...

BACKGROUND The performance of nebulizers varies with the design type as well as the breathing patterns of various age groups. The present study quantified aerosol delivery using spontaneously breathing parameters of a small child (2-4 years) by a lung simulator to determine the influence of nebulizer type, actuation mechanisms, and pediatric aerosol masks. METHODS Three types of nebulizer (c...