The ability of gifted composers such as Mozart to create complex multipart musical compositions with relative ease suggests a highly efficient mechanism for generating multiple parts simultaneously. Computational models of human music composition can potentially shed light on how such rapid creativity is possible. This paper proposes such a model based on the idea that the multiple threads of a...

Nonexercise activity thermogenesis (NEAT) is the energy expended for everything that is not sleeping, eating, or sports-like exercise. It includes the energy expended walking to work, typing, performing yard work, undertaking agricultural tasks, and fidgeting. NEAT can be measured by one of two approaches. The first is to measure or estimate total NEAT. Here, total daily energy expenditure is m...

Iron is essential for bacterial survival, being required for numerous biological processes. NEAr-iron Transporter (NEAT) domains have been studied in pathogenic Gram-positive bacteria to understand how their proteins obtain heme as an iron source during infection. While a 2002 study initially discovered and annotated the NEAT domain encoded by the genomes of several Gram-positive bacteria, ther...

The difficulty of sustaining ICT4D projects in developing nations is a formidable issue encountered by project managers. Addressing this issue is vital given reasons such as the opportunity cost of IT investment failure in developing-world contexts. This paper presents a study which explores the sustainability of ICT4D projects via a case study of a large-scale, nation-wide, government sector I...

In vertebrates, most iron is present as heme or is chelated by proteins. Thus, Gram-positive pathogens such as Staphylococcus aureus have evolved an iron-regulated surface determinant (Isd) system that transports heme across thick cell walls into the cytoplasm. Recent studies have demonstrated that heme is rapidly transferred between the NEAr Transporter (NEAT) domains of the Isd system, despit...