BACKGROUND Weight loss has been found to improve or resolve cardiovascular comorbidities. There is a significant need for reversible device approaches to weight loss. METHODS Non-constrictive cuff (NCC) is made of implantable silicone rubber with an internal diameter greater than the duodenum. Ten or 11 NCC were individually mounted along the duodenum from the pyloric sphincter toward the dis...

In this study, nanocrystalline cellulose (NCC) was used for increasing the bonding strength of urea-formaldehyde (UF) resin adhesive, with a reduction of formaldehyde (HCHO) emissions. The surface of NCC was modified by 3-aminpropyltriethoxysilane (APTES) and 3-methacryloxypropyltrimethoxysilane (MPS) for the lack of compatibility with UF resin adhesive. The modified NCC was characterized by X-...

Blood pressure (BP) normally dips during sleep, and nondipping increases cardiovascular risk. Hydrochlorothiazide restores the dipping BP profile in nondipping patients, suggesting that the NaCl cotransporter, NCC, is an important determinant of daily BP variation. NCC activity in cells is regulated by the circadian transcription factor per1. In vivo, circadian genes are entrained via the hypot...

OBJECTIVE The diagnosis of neurocysticercosis (NCC) remains problematic because of the heterogeneity of its clinical, immunological, and imaging characteristics. Our aim was to develop and assess a new set of diagnostic criteria for NCC, which might allow for the accurate detection of, and differentiation between, parenchymal and extraparenchymal disease. METHODS A group of Latin American NCC...

AIM We wanted to characterize the clinical profile and outcome of pregnancy in women with epilepsy due to neurocysticercosis (NCC) enrolled in the Indian Registry of Epilepsy and Pregnancy (IREP). METHODS We identified all women with NCC in the IREP between January 2000 and September 2005. Age- and parity-matched patients without NCC were identified from the respective centers of IREP for com...

A function is non-cooperative computable [NCC] if honest agents can compute it by reporting truthfully their private inputs, while unilateral deviations by the players are not beneficial: if a deviation from truth revelation can mislead other agents, then the deviator might end up with a wrong result. Previous work provided full characterization of the boolean functions which are non-cooperativ...

Hypertension is a leading cause of morbidity and mortality worldwide, and disordered sodium balance has long been implicated in its pathogenesis. Aldosterone is perhaps the key regulator of sodium balance and thus blood pressure. The sodium chloride cotransporter (NCC) in the distal convoluted tubule of the kidney is a major site of sodium reabsorption and plays a key role in blood pressure reg...

The thiazide-sensitive NaCl cotransporter (NCC) plays a key role in renal salt reabsorption and the determination of systemic BP, but the molecular mechanisms governing the regulation of NCC are not completely understood. Here, through pull-down experiments coupled to mass spectrometry, we found that γ-adducin interacts with the NCC transporter. γ-Adducin colocalized with NCC to the distal conv...

The early Neoproterozoic sediments in the southern–southeastern (S-SE) North China Craton (NCC) are critical paleogeographic reconstruction. We present new detrital zircon U–Pb–Hf data of five sandstone samples from Sangwon Supergroup SE-NCC and Wufoshan Group S-NCC. integrate published U–Pb to appraise their provenance. dataset constrains maximum depositional age be ca. 1.0 Ga. similar provena...

THERE IS NO DOUBT ABOUT THE clinical importance of the thiazide-sensitive sodium chloride cotransporter (NCC). The NCC exists exclusively in the distal convoluted tubule and is responsible for 5–10% of NaCl reabsorption by the kidney. The efficacy of an inhibitor of the NCC, chlorothiazide, in lowering blood pressure was first demonstrated in 1958 (3), and thiazide diuretics continue to serve a...